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Oncologic Effect of Oral Fluorouracil in Hormone Receptor-Negative T1a Node-Negative Breast Cancer Patients

Kim M, Ahn S, Son B, Lee J, Koh B, Sohn B, Lee S, Kim HJ

PURPOSE: As 5-fluorouracil (5-FU) has previously exhibited antitumor activity and few adverse effects in the treatment of breast cancer, we aimed to specifically assess the benefits of orally administered 5-FU...
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Evaluation of Prognostic Factors and Validation of Tumor Response Ratios after Neoadjuvant Chemotherapy in Patients with Breast Cancer

Moon T, Cho DH, Youn JM, Lee JB, Bae JW, Jung SP

PURPOSE: In the treatment of breast cancer, neoadjuvant chemotherapy (NAC) is useful to reduce breast cancer size before surgical intervention. Patients who achieve a pathologic complete response (pCR) to NAC...
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Effects of Less than 60 Days Delay in Surgery on Tumor Progression and Survival Outcomes in Invasive Breast Cancer Patients

Lee J, Son BH, Lee S, Lee JW, Ko BS, Kim HJ, Kim J, Chung IY, Sohn G, Ahn SH

PURPOSE: The effect of delays in surgical treatment on survival outcomes in patients with breast cancer remains uncertain, but it is an issue of importance to both patients and clinicians....
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Prediction of Axillary Nodal Status according to the Axillary Lymph Node to Primary Breast Tumor Maximum Standardized Uptake Value Ratio on 18F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography

Sun WY, Choi YJ, Song YJ

PURPOSE: This study aimed to evaluate the usefulness of the axillary lymph node to primary breast tumor maximum standardized uptake value (SUVmax) ratio in 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography...
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The Molecular Subtype Dependent Effect of Concurrent Radiotherapy and Systemic Therapy on Breast Cancer: Analysis of a Human In Vivo Model of Metastatic Brain Lesions

Hwang SH, Choi HS, Kim YG, Kim JH, Seong MK, Jang WI, Youn SM, Kim HA, Noh WC

PURPOSE: The molecular subtype of breast cancer is an important predictive factor. Therefore, we investigated the effects of concurrent or serial radiotherapy and systemic therapy on metastatic brain lesions according...
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Preoperative Breast Magnetic Resonance Imaging for the Assessment of the Size of Ductal Carcinoma In Situ

Rayzah M, Ryu JM, Lee JE, Alramadhan M, Han B, Yi HW, Park S, Paik HJ, Nam SJ

PURPOSE: The purpose of this study was to determine whether magnetic resonance imaging (MRI) could assess the size of ductal carcinoma in situ (DCIS) more accurately compared to mammography and...
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Reliability of Core Needle Biopsy in Evaluating Estrogen Receptor, Progesterone Receptor, and Human Epidermal Growth Factor Receptor 2, and Ki-67 Status

Sohn HJ, Kim HS, Park SJ, Shin HC

PURPOSE: The preoperative determination of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2), and Ki-67 expression status is crucial because these factors influence the...
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Analysis of the Relationship between Body Mass Index and Breast Cancer Incidence in Korean Women

Kang HS, Han J, Kim J, Lee HB, Shin HC, Han W, Noh DY, Moon HG

PURPOSE: Obesity in women has been shown to have correlation with breast cancer incidence. The proportion of Korean women who are obese has increased recently. However, there is no large-scale...
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Distress and Quality of Life for Breast Cancer Survivors during Follow-Up Periods in Korea

Jo HC, Kim ET, Min JW

PURPOSE: Few studies have reported postdiagnosis differences in distress and quality of life (QOL) for breast cancer (BC) survivors. Here we investigated the differences in distress and QOL for BC...
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Comparison of Prognosis according to Tumor Size in Small Breast Cancer with Lymph Node Involvement

Han HS, Ryu JM, Kim I, Paik HJ, Park S, Bae SY, Lee SK, Yu J, Lee JE, Nam SJ, Kim SW

PURPOSE: Larger tumor size and more extensive lymph node (LN) involvement have been considered independent factors for poor prognosis of breast cancer. We evaluated whether smaller tumor size may be...
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Predictive Factors of Residual Metastatic Axillary Lymph Nodes after Neoadjuvant Chemotherapy in Node-Positive Breast Cancer

Lee HY, Park HY, Kang JG

PURPOSE: Sentinel lymph node biopsy (SLNB) has been a reliable technique in breast cancer staging. However, some authors reported that SLNB after neoadjuvant chemotherapy (NAC) could lead to low identification...
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Selective B-RAF V600E Inhibitor PLX4032 Inhibits the Growth of Breast Cancer Cell Lines through Cell Cycle Arrest

Yang EY, Park MY, Jung SM, Nam SE, Kwon JO, Yoo YB, Yang JH, Park KS

PURPOSE: Breast cancer is the most common invasive cancer and the second common cause of death among women worldwide. Many researchers have focused on the effective treatment of advanced breast...
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