- BRCA1 Reversion Mutation Confers Resistance to Olaparib and Camrelizumab in a Patient with Breast Cancer Liver Metastasis
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Pan JN, Lei L, Ye WW, Wang XJ, Cao WM
- KMID: 2522098
- J Breast Cancer.
- 2021 Oct;24(5):474-480.
- doi: 10.4048/jbc.2021.24.e39
Reversion mutations are associated with clinical resistance to poly(ADP-ribose) polymerase inhibitors (PARPi). Here, we describe the detection of a BRCA1 reversion mutation in a 39-year-old woman with metastatic breast cancer... -
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- Successful Pre-Operative Local Control of Skin Invasion of Breast Cancer Using a Combination of Systemic Chemotherapy and Mohs Paste
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Takeuchi M, Katsuki T, Yoshida K, Onoda M, Iwamura M, Inokuchi T, Furutani A, Katoh T, Kawano K, Hirata K
- KMID: 2522099
- J Breast Cancer.
- 2021 Oct;24(5):481-490.
- doi: 10.4048/jbc.2021.24.e46
Locally advanced breast cancer (tumor > 5 cm, widespread infiltration of the skin and muscle, or metastases to lymph nodes) is difficult to resect by surgery, and even when it... -
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- Long Noncoding-RNA Component of Mitochondrial RNA Processing Endoribonuclease Promotes Carcinogenesis in Triple-Negative Breast Cancer Cells via the Competing Endogenous RNA Mechanism
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Qi L, Sun B, Yang B, Lu S
- KMID: 2522094
- J Breast Cancer.
- 2021 Oct;24(5):428-442.
- doi: 10.4048/jbc.2021.24.e42
Purpose: Triple-negative breast cancer (TNBC) is a subtype of breast cancer. Increasing evidence supports that dysregulation of long noncoding RNAs (lncRNAs) plays a vital role in cancer progression. RNA component... -
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- Longitudinal Intravital Imaging of Tumor-Infiltrating Lymphocyte Motility in Breast Cancer Models
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Park I, Hong S, Seok J, Lucia SE, Song E, Kim M, Kong E, Seo H, Hwang Y, Ahn S, Kim S, Jang DH, Lee JH, Park SH, Kim P, Jo YH
- KMID: 2522097
- J Breast Cancer.
- 2021 Oct;24(5):463-473.
- doi: 10.4048/jbc.2021.24.e40
Immunoreactive dynamics of tumor-infiltrating lymphocytes (TILs) within the tumor microenvironment in breast cancer are not well understood. This study aimed to investigate the spatiotemporal cellular dynamics of TILs in breast... -
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- Histological Findings of Mammary Gland Development and Risk of Breast Cancer in BRCA1 Mutant Mouse Models
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Kim H, Moon WK
- KMID: 2522096
- J Breast Cancer.
- 2021 Oct;24(5):455-462.
- doi: 10.4048/jbc.2021.24.e44
Purpose: The breast cancer susceptibility gene, BRCA1, is involved in normal development and carcinogenesis of mammary glands. Here, we aimed to evaluate the relationship between histological findings of mammary gland... -
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- Neutrophil to Lymphocyte Ratio after Treatment Completion as a Potential Predictor of Survival in Patients with Triple-Negative Breast Cancer
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Kim KM, Choi HS, Noh H, Cho IJ, Lim ST, Lee JI, Han A
- KMID: 2522095
- J Breast Cancer.
- 2021 Oct;24(5):443-454.
- doi: 10.4048/jbc.2021.24.e43
Purpose: Triple-negative breast cancer (TNBC) has been associated with worse prognosis, and biomarkers are needed to identify high-risk patients who may benefit from clinical trials or escalated treatment after completion... -
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- Fatty Liver in Hormone ReceptorPositive Breast Cancer and Its Impact on Patient's Survival
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Taroeno-Hariadi KW, Putra YR, Choridah L, Widodo I, Hardianti MS, Aryandono T
- KMID: 2522093
- J Breast Cancer.
- 2021 Oct;24(5):417-427.
- doi: 10.4048/jbc.2021.24.e41
Purpose: Long-term estrogen inhibition may cause fatty liver disease (non-alcoholic fatty liver disease; NAFLD) among other adverse conditions such as osteoporosis, climacteric symptoms, thromboembolism, dyslipidemia, and metabolic syndrome. The prevalence... -
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