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In regard to “The Italian Association of Radiotherapy and Oncology Recommendation for Breast Tumor Recurrence: Grades of Recommendation, Assessment, Development and Evaluation Criteria”

Hannoun-Levi JM, Gutierrez C, Polgar C, Strnad V, on behalf of the Breast Cancer-Working Group (BCWG) of the Groupe Européen de Curiethérapie-European Society for Radiotherapy and Oncology (GEC-ESTRO)

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The Role of STAT1 in T Helper Cell Differentiation during Breast Cancer Progression

Banik S, Rakshit S, Sarkar K

Members of the signal transducer and activator of transcription (STAT) protein family are intracellular transcription factors that facilitate several facets of cellular immunity, proliferation, apoptosis, and differentiation. They are principally...
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Ectopic Male Breast Cancer in Suprapubic Area That Relapsed with Hematogenous Metastasis

Byon JH, An AR, Shin JY, Choi EJ

Tough ectopic male breast cancer is extremely rare, non-axillary ectopic male breast cancer is even rare. To date, the natural course and prognosis of this disease are not fully understood. Consequently,...
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Impact of Trastuzumab on Ipsilateral Breast Tumor Recurrence for Human Epidermal Growth Factor Receptor 2-Positive Breast Cancer after BreastConserving Surgery

Cheun JH, Won J, Jung JG, Kim HK, Han W, Lee HB

Purpose: Trastuzumab is effective in early and advanced human epidermal growth factor receptor 2 (HER2)-positive breast cancer. However, few studies have reported the effect of trastuzumab on ipsilateral breast tumor...
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Usefulness of 3-Dimensional-Printed Breast Surgical Guides for Undetectable Ductal Carcinoma In Situ on Ultrasonography: A Report of 2 Cases

Wu ZY, Lee YJ, Shin Y, Choi S, Baek SY, Chun JW, Albinsaad LS, Choi WJ, Kim N, Ko B

Tumor localization is challenging in the context of ductal carcinoma in situ (DCIS) treated with breast-conserving surgery. Conventional localization methods are generally performed under the guidance of ultrasonography or mammography...
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HOXD Antisense Growth-Associated Long Noncoding RNA Promotes TripleNegative Breast Cancer Progression by Activating Wnt Signaling Pathway

Zhang C, Yang Y, Yi L, Paizula X, Xu W, Wu X

Purpose: Triple-negative breast cancer (TNBC) is the most lethal subtype of breast cancer owing to high heterogeneity, aggressive nature, and lack of treatment options, which has a substantial deleterious effect...
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Long Non-Coding RNA NORAD Inhibits Breast Cancer Cell Proliferation and Metastasis by Regulating miR-155-5p/ SOCS1 Axis

Liu W, Zhou X, Li Y, Jiang H, Chen A

Purpose: Non-coding RNA activated by DNA damage (NORAD) has been reported to be a cancer-related long non-coding RNA (lncRNA) implicated in the progression of several cancers; however, its role in...
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A Nationwide Study on the Incidence of Breast Cancer in Korean Women with Osteoporosis Receiving Raloxifene Treatment

Lee J, Lee JS, Lee JE, Kim Z, Han SW, Hur SM, Choi YJ, Park S

Purpose: Raloxifene is a selective estrogen receptor modulator (SERM), and raloxifene treatment for osteoporosis is reimbursable under the Korean National Health Insurance. Evidence suggests that SERMs use reduces the risk of...
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Immediate Reconstruction of Large Ptotic Breasts following Vertical Reduction Pattern Nipple-Sparing Mastectomy

Chung JH, Hwang YJ, Jung SP, Park SH, Yoon ES

Purpose: Women with large and/or ptotic breasts are generally not considered candidates for nipple-sparing mastectomy because of concerns regarding the high incidence of postoperative complications including ischemic complications. Therefore, we...
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Programmed Death Ligand 1 Immunohistochemistry in TripleNegative Breast Cancer: Evaluation of Inter-Pathologist Concordance and Inter-Assay Variability

Purpose: The programmed death ligand 1 (PD-L1) SP142 assay with a 1% immune cell (IC) cutoff is approved for the selection of advanced triple-negative breast cancer (TNBC) patients for atezolizumab...
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The Italian Association of Radiotherapy and Oncology Recommendation for Breast Tumor Recurrence: Grades of Recommendation, Assessment, Development and Evaluation Criteria

Bottero M, Borzillo V, Pergolizzi S, Jereczek-Fossa BA, Ippolito E, Frezza GP, Fortunato L, Corvò R, Pappagallo GL, Arcangeli S, Magrini SM, D'Angelillo RM

Salvage mastectomy is currently considered the standard of care for ipsilateral breast tumor recurrence (IBTR) after breast-conserving surgery (BCS) and postoperative radiotherapy (RT). Alternative treatment options for these patients, such...
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