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The Reliability and Validity of World Health Organization Quality of Life Assessment Instrument (WHOQOL) in Patients with Breast Cancer: Physical Domain and Depression

Park EJ, Moon EJ, Choi H, Oh SJ, Jeon YW, Han SI

PURPOSE: This study was designed to investigate the reliability and validity of the World Health Organization Quality of Life Assessment Instrument (WHOQOL) in patients with breast cancer according to depressive...
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Intrapleural Paclitaxel Chemotherapy in the Treatment of Breast Cancer-Related Metastatic Malignant Pleural Effusion

Park SY, Choi JE, Jeon MH, Kang SH, Lee SJ

Malignant pleural effusion in breast cancer has been associated with poor prognosis. The response rate of local treatment has been very low and in some case, complications have resulted in...
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Efficacy of Breast Ultrasonography for Detection of Local, Regional, and Contralateral Recurrence of Breast Cancer

Bae DS, Han W, Moon HG, Moon WK, Cho N, Kim H, Ahn SK, Oh SK, Youn YK, Noh DY

PURPOSE: Breast ultrasonography (US) is not recommended for recurrence monitoring after breast cancer surgery due to the lack of evidence for its advantage. The purpose of this study was to...
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Charlson Comorbidity Index as a Predictor of Long-Term Survival after Surgery for Breast Cancer: A Nationwide Retrospective Cohort Study in South Korea

Woo HK, Park JH, Kang HS, Kim SY, Lee SI, Nam HH

PURPOSE: The aim of this article was to evaluate the impact of the Charlson Comorbidity Index (CCI) on long-term survival after surgery for breast cancer in South Korea. METHODS: The study...
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Single-Port Access Laparoscopic Prophylactic Bilateral Salpingo-Oophorectomy in BRCA-Positive Breast Cancer Patient: A Case Report

Kim TJ, Choi MY, Lee SK, Hur SM, Kim S, Koo MY, Bae SY, Cho DH, Choe JH, Kim JH, Kim JS, Kim BG, Bae DS, Lee JE, Nam SJ, Yang JH

For women with a BRCA 1/2 mutation, prophylactic bilateral salpingo-oophorectomy (BSO) is known to reduce the risk of developing both ovarian and breast cancer. The increasing interest in hereditary breast...
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Painless Posterior Thigh Mass as a Presentation of Metastatic Breast Cancer

Cho HM, Ko MS, Lee JH, Jung WS, Choi HJ, Oh SJ, Suh YJ

Soft tissue metastasis clinically presenting as either painless subcutaneous or painful intramuscular nodules is extremely rare and may lead to an errant clinical suspicion of sarcoma. In general, most soft...
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Evaluation of Phase-Contrast Microscopic Imaging with Synchrotron Radiation in the Diagnosis of Breast Cancer and Differentiation of Various Breast Diseases: Preliminary Results

Jeong YJ, Bong JG, Kim HT, Kim JK, Oh HK, Huang JY, Park SH

PURPOSE: A significant improvement of imaging using synchrotron radiation (SR) is obtained by introducing phase-contrast technique. This technique provides greatly enhanced contrast and good soft tissue discrimination with high spatial...
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The Clinical Use of Low-Dose Multidetector Row Computed Tomography for Breast Cancer Patients in the Prone Position

Lee WJ, Seo BK, Cho PK, Yie A, Cho KR, Woo OH, Cha SH, Son GS, Lee GY

PURPOSE: To investigate the clinical use of low-dose multidetector row computed tomography (MDCT) for staging of invasive breast cancers with patients in the prone position. METHODS: Three hundred twenty-two patients with...
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A Study Regarding Predictive Factors for Malignancy of Papillary Lesions on Core Needle Biopsy of the Breast

Ha MH, Lee JA, Lee SG, Son GS, Lee ES, Bae JW

PURPOSE: Diagnosing benign or malignant papillary lesions of the breast through core needle biopsy (CNB) is often difficult. The purpose of this study was to identify the predictive factors of...
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Molecular Mechanism of the G2/M Arrest in Breast Cancer Cell Lines (T47D and MDA-MB231) Induced by Genistein

Park JY, Kang KS, Sohn YK

PURPOSE: To analyze the effect of the growth control on human breast cancer cells with genistein treatment and to investigate the mechanism of genistein-induced G2/M arrest in T47D and MDA-MB231...
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Clinicopathological Characteristics and Factors Affecting Recurrence of Ductal Carcinoma In Situ in Korean Women

Kim JS, Moon HG, Ahn SK, Min JW, Shin HC, Kim HS, Yeom CK, Ha SH, Chie EK, Han W, Noh DY

PURPOSE: As breast cancer screening becomes more popular in Korea, incidence of ductal carcinoma in situ (DCIS) of breast has increased to more than 10% of all breast cancer diagnosed....
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Use of Antidepressants in Patients with Breast Cancer Taking Tamoxifen

Kim SH, Lee MR, Lee KC, Lee JH, Kwon HC, Kim DC, Lee KW, Cho SH

Tamoxifen, a selective estrogen modulator has been used for more than three decades to treat all stages of estrogen receptor (ER)-positive breast cancer and to prevent the disease. Tamoxifen is...
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Hormonal Changes during Extended Letrozole Treatment after Completion of 5 Years of Tamoxifen in Premenopausal Patients with Breast Cancer who Became Postmenopausal

Cho JY, Kim HJ, Lee JW, Yu JH, Koh BS, Yi OV, Son BH, Ahn SH

PURPOSE: Extended treatment with aromatase inhibitors (AIs) after tamoxifen has shown effectiveness in postmenopausal patients with breast cancer. However it is very difficult to start on AIs for patients who...
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Phosphorylated Akt and Phosphorylated mTOR Expression in Breast Invasive Carcinomas: Analysis of 530 Cases

An J, Jeong H, Lee Y, Woo SU, Seo JH, Kim A

PURPOSE: The phosphatidylinositol 3-kinase (PI3K)/Akt/mammalian target of rapamycin (mTOR) pathway has a central role in regulation of cell proliferation, differentiation, motility and survival. This pathway has recently generated great interest...
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The Change of Practice Patterns of the Hereditary Breast Cancer Management in Korea after the Korean Hereditary Breast Cancer Study

Kang E, Ahn SH, Noh WC, Noh DY, Jung Y, Kim LS, Choi DH, Suh YJ, Kim KS, Lee JE, Lee MH, Nam SJ, Moon BI, Son BH, Yang JH, Yom CK, Kim SY, Park SK, Kim SW, Korean Breast Cancer Society

PURPOSE: The objective of this study was to evaluate the change in the practice patterns for managing hereditary breast and ovarian cancer (HBOC) among Korean physicians after the Korean Hereditary...
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One-step Nucleic Acid Amplification (OSNA): Intraoperative Rapid Molecular Diagnostic Method for the Detection of Sentinel Lymph Node Metastases in Breast Cancer Patients in Korean Cohort

Choi YL, Ahn SK, Bae YK, Park IA, Min JW, Lee KW, Bae JH, Han W, Choi JE, Cho EY, Kim S, Lee HS, Nam SJ, Lee JE, Lee SJ, Noh DY, Yang JH

PURPOSE: Sentinel lymph node (SLN) biopsy has become a standard procedure in breast cancer patient management. Accurate intraoperative assessment of metastasis of SLNs is essential for appropriate selection to avoid...
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