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The evidence for adjuvant taxanes in early breast cancer

Basi S, Mackey JR

Adjuvant chemotherapy plays an important role in improving disease free and overall survival in women with high-risk early stage breast cancer. While more than seventy thousand women have enrolled in...
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Inflammatory Myofibroblastic Tumor of the Breast

Park IK, Yoon DS, Kim YM, Park HD, Min SK

Inflammatory myofibroblastic tumor (IMT) is an uncommon, tumorlike lesion that occurs at a number of body sites. Although the lung is the best known and most commonly organ, IMT has...
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Sparganosis : two cases report

Hwang MR, Park YL, Bae WG

Sparganosis is not a common disease. Uncooked snake or frog, infected water and fresh water fish are the usual important source of sparganosis. Most cases of sparganosis are found in...
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Application Patterns of Sentinel Lymph Node Biopsy in Korean Breast Cancers

Yang JH, Kim DG, Woo SW, Kim JH, Nam SJ

PURPOSE: The sentinel lymph node biopsy (SLNB) has revolutionized the management of breast cancer. Since October 1995, when we first applied the SLNB for treatment of breast cancer, it has...
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Survival Analysis of Korean Breast Cancer Patients Diagnosed between 1993 and 2002 in Korea: A Nationwide Study of the Cancer Registry

The Korean Breast Cancer Society

PURPOSE: Breast cancer has been the most prevalent cancer among Korean women since 2001, yet the nationwide survival data for cancer patients has not been examined. The purpose of the...
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Correlation between C-MYC and HER2 Amplification in Non-selected Breast Cancers

Ahn SK, Kwak K, Shin E, Kim H, Kim J, Park K, Han S

PURPOSE: c-myc and HER2 have been reported be amplified in 20% to 30% of clinical breast cancers and appears to be related with poor clinical outcome. The relationship between amplification...
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The Efficacy of Oral Combination Chemotherapy of 5'-DFUR and Cyclophosphamide for Metastatic Breast Cancer

Park MH, Yoon JH, Jegal YJ

PURPOSE: A sufficient response rate and good compliance are both important for instituting chemotherapy to treat metastatic breast cancer. Effective oral chemotherapy regimens have long been studied to improve patients'...
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Apoptotic Effect of the Cyclooxygenase-2 Inhibitor Celecoxib on Human Breast Cancer MDA-MB 468 Cells

Cha Y, Ko HS, Kim H, Kim JR, Kim JH

Purpose: Cyclooxygenase (COX) is an enzyme that catalyzes the conversion of arachidonic acid to prostaglandins. The inducible form, COX-2, is induced by such proinflammatory and mitogenic stimuli as cytokines and...
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Surgical Treatment of Locoregional Recurrence in Breast Cancer

Kim JK, Son BH, Kwak BS, Hwang UK, Kim HJ, Lee JS, Hong SJ, Jung MS, Ahn SD, Ahn SH

PURPOSE: The locoregional recurrence (LRR) in breast cancer, without distant metastasis has traditionally been regarded as a predictor of subsequent distant metastasis. This study was designed to attain the survival...
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The Result of Evaluation According to Radioactivity of Sequential Sentinel Nodes Biopsy in Breast cancer

Oh JW, Jung SY, Hur H, Lee JD, Kim SI, Kim SH, Yang WI, Yun MJ, Park BW

PURPOSE: Radio-guided sentinel node biopsy has become a standard method for evaluating the axillary status. However, there is no guideline for the optimum extent of sentinel lymphadenectomy. The object of...
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Expression of the Markers for the Mammary Stem Cells and the Cellular Lineages of the Mammary Gland on Ductal Carcinoma In Situ

Jo BH, Kim HJ, Kim YJ, Park Y, Lee IK, Kim DI, Lee WH, Yoon SO

PURPOSE: Breast Cancer is an inter-tumoral and intra-tumoral heterogeneous disease. It remains unclear whether this heterogeneity results from different target cells or from different subsets of genetic abnormalities, otherwise from...
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Inhibitory Effect on Angiogenesis of a Selective Cyclooxygenase-2 Inhibitor with using Mouse Mammary Tumor cells

Kim HM, Woo HD, Sohn DM, Kim SY, Lim CW, Park RK, Jung SP, Lee MH

PURPOSE: Angiogenesis plays a key role in the growth and metastasis of malignant tumor. Angiogenesis is reportedly enhanced by prostaglandins (PGs). Cyclooxygenase (COX)-2 is an inducible enzyme that catalyzes the...
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