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Validation and Controversy of Sentinel Node Biopsy for Breast Cancer

Motomura K, Egawa C, Komoike Y, Kataoka T, Nagumo S, Koyama H, Inaji H

Sentinel node biopsy has become a promising technique to accurately stage breast cancer patients with less morbidity than axillary lymph node dissection. However, many problems remain, such as the ideal...
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Nationwide Korean Breast Cancer Data of 2004 Using Breast Cancer Registration Program

The Korean Breast Cancer Society

PURPOSE: Since 1996, the Korean Breast Cancer Society has analyzed and reported the nation wide breast cancer data on a biannual basis. The purpose of this study is to evaluate...
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A Case-Control Study on the Risk Factors of Breast Cancer in Korean Women

Yi MS, Youn HJ, Jung SH

PURPOSE: The annual incidence of breast neoplasms continues to rise, but only a few studies on the risk factors for breast neoplasms in Korea have been conducted. The aim of...
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Evaluation of Computer Aided Diagnosis (CAD) in the Interpretation of Mass Lesions seen on Breast Sonography

Yoon TI, Park SH, Byon JS, Park HB

PURPOSE: Sonography for the diagnosis of breast cancer, is important in Korea because Oriental women have denser breast and their breast cancer generally occurs at a younger age. We investigate...
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Up-regulation of P13K/Akt Signaling by 17 beta-estradiol through Activation of Estrogen Receptor-alpha in Breast Cancer Cells

So MC, Hwang HP, Lee CH, Youn HJ, Jung SH, Kim JC

PURPOSE: Estrogen stimulates cell proliferation in breast cancer, the biological effects of which are mediated through two intracellular receptors: estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta). However, the actual role...
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The Prognosis of Breast Cancer Patients with 10 or more Positive Lymph Nodes

Bu DS, Paik NS, Moon NM, Kim MS, Yang KM, Noh WC

PURPOSE: According to the staging system for breast cancer by the 2003 revised American Joint Committee on Cancer (AJCC), the patients with 10 or more positive axillary nodes are classified...
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The Loss of p16(ink4)Expression is Strongly Associated with Hyperme thylation-Related Inactivation in Breast Carcinoma

Gong G, Kim MJ, Shim YH, Kang GH, Ahn SH, Ro JY

PURPOSE: The loss of p16 protein has been frequently detected in breast carcinoma, but genetic alterations are infrequent. CpG islands of methylation within the p16 promotor have been identified as...
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Biologic behavior of E-cadherin in Invasive Ductal Carcinoma of the Breast

Lee SG, Bae JW, Kim JH, Chae YS, Cho KR, Lee JB, Son GS, Koo BH

PURPOSE : E-cadherin is a tumor suppressor adhesion molecule that has an anti-invasive role and it is often considered as a useful marker for differentiating the lobular types from the...
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Utiliy of Breast Sentinel Lymph Node Biopsy Using the Day-Before or the Same-Day Subareolar Injection of (99m)Tc-Tin Colloid

Kim KS, Kim YH, Paik NS, Kim MS, Choi CW, Moon NM, Noh WC

PURPOSE: The aims of this study were to examine the feasibility of sentinel lymph node (SLN) biopsy using the day-before-surgery or the same-day subareolar injection of (99m)Tc-Tin colloid, and to...
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Expression of Interferon Regulatory Factors in Breast Cancer Tissue

Yoon JH, Park MH, Cho MH, Jaegal YJ, Park CS

PURPOSE: As neoplasia is the result of unbalanced cell growth and cell death, alternations in the growth control pathway including the immunity within the individual host-tumor relationship has been attributed...
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Preoperative Evaluation of Lymph Node Metastasis with Using Ultrasonography for Examining the Axilla in Early Stage Breast Cancer

Hwang SE, Moon WK, Cho N, Han W, Kim SW, Shin HJ, Hwang KT, Lee JE, Youn YK, Oh SK, Noh DY

PURPOSE: The axillary lymph node status is the most significant prognostic factor in breast cancer. The development of tools to accurately evaluate the axillary lymph node status with less morbidity...
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The recurrence rate, risk factors and recurrence patterns after surgery in 3700 patients with operable breast cancer

Son BH, Ahn SH, Kwak BS, Kim JK, Kim HJ, Hong SJ, Lee JS, Yun S, Kim SB, Ahn JH, Kim WK, Ahn SD, Kim HH, Gong GY

PURPOSE: This study was aimed at evaluating the recurrence rate and recurrence patterns after surgically treating for patients with operable breast cancer. METHODS: From 1992 to 2002, 3700 patients with...
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