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Flavonoids: A new generation molecule to stimulate programmed cell deaths in cancer cells

Venkatarame Gowda Saralamma V, Kim EH, Lee HJ, Raha S, Lee WS, Heo JD, Lee SJ, Won CK, Kim GS

Programmed cell death (PCD) is decisive in eliminating affected cells in human cancers, whereas there are increasing cases of cancer-related death due to side effects of modern treatment methods. There...
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Database construction of small–molecule inhibitors as bovine viral diarrhea virus (BVDV) RNA-dependent RNA polymerase: a cheminformatics approach

Chai HH, Choi BH, Park JE, Kim UH, Cho YM, Lim D

Bovine viral diarrhea virus (BVDV) is a major pathogen that may be one of the main reasons for economic losses in the livestock industry. BVDV is a well-characterized member of...
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Interspecies pharmacokinetic scaling of 11-hydroxyaclanomycin X based on animal data

Shin DH, Lee SY, Jeong SW, Park CW, Chung YB

The pharmacokinetics of 11-Hydroxyaclacinomycin X (HAMX), a novel anthracycline, were investigated after intravenous bolus administration in mice, rats, rabbits and dogs. Based on animal data, we predicted the following human...
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Passage-dependent expression of inward rectifying potassium current in human umbilical cord vein-derived mesenchymal stem cells

Park KS, Chai YG, Kim Y

Although stem cells are used as important cell therapies in regenerative medicine, the electrophysiological problems that arise in the expansion of cells have not been known much. This study was...
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Immunomodulatory effects of mixed Weissella cibaria JW15 with water extract of black soybean and burdock on Listeria monocytogenes infection in mice.

Park HE, Lee WK

The objective of this study is to assess immunomodulatory effects of mixed Weissella (W.) cibaria JW15 strain with water extract of black soybean (Glycine max) and burdock (Arctium lappa) on...
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