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RND efflux pump systems in Acinetobacter, with special emphasis on their role in quorum sensing

Subhadra B, Oh MH, Choi CH

Acinetobacter is an important opportunistic, multidrug resistant pathogen causing majority of nosocomial infections worldwide. The multidrug resistance is attributed by a plethora of efflux pumps and the overexpression of the...
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Delafloxacin, a New Miracle in Antibiotics Armamentarium for Bacterial Infections

Rahman MS, Koh YS

The persistent antibiotics resistant issue has emerged as an influencing factor to deteriorate community health. So, new antibiotics development is urgent for the treatment of bacterial infections. Alternatively, delafloxacin is...
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Effector Pathways of Toll-like Receptor-inducible Innate Immune Responses in Macrophages

Jo EK, Suh HW, Park JK

Toll-like receptors (TLR) are well-characterized pattern recognition receptors that can recognize and respond to diverse pathogen-associated or danger-associated molecular patterns during infection. TLR signaling in macrophages triggers in the intracellular...
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Apolipoprotein E Genotype and Expression Correlated with Hepatitis C Virus Genotype and Infection

Park GN, Jo HJ, Kim HR, Kim MJ, Shin KA, Hong SB, Chang KS

The hepatitis C virus (HCV) is a globally prevalent human pathogen that causes persistent liver infections in most infected individuals. Several studies reported that HCV particles are enriched in apolipoprotein...
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