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A20 Protects Against Arthritis by Regulation of the NLRP3 Inflammasome

Manzoor Z, Koh YS

Rheumatoid arthritis is an autoinflammatory disease that primarily affects joints and is characterized by pervasive joint inflammation. A20/Tumor necrosis factor, alpha-induced protein 3 (Tnfaip3) inhibits activation of nuclear factor kappa-light-chain-enhancer...
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Immunomodulatory Roles of PE/PPE Proteins and Their Implications in Genomic Features of Mycobacterium tuberculosis

Choi SY, Shin SJ

Tuberculosis, caused by Mycobacterium tuberculosis (Mtb), remains a notorious cause of human death worldwide. A deeper understanding of the proline-glutamate (PE) and proline-proline-glutamate (PPE) families, which compromise 10% of the...
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Influence of the Host Factors on Human Papillomavirus Infection and Vaccine Efficacy

Sohn SH, Nam JH

Human papillomavirus (HPV) is associated with cervical cell changes, genital warts, recurrent respiratory papillomatosis, laryngeal papillomatosis, head and neck cancer, and cervical cancer. Two commercial HPV vaccines have successfully been...
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Current and Next-generation Vaccines against Human Papillomaviruses

Kim YH

Human papillomaviruses (HPVs) infect the squamous epithelium, and cause skin warts, genital warts and cancers, including uterine cervical cancer. Amongst the enormously diverse types of HPVs, HPV16 and HPV18 are...
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Protein Expression of the Bombyx mori Decapentaplegic Gene using the Baculovirus Expression Vector System

Jeong ST, Park SW

The Bombyx mori decapentaplegic gene is one of the conserved genes in vertebrate and invertebrates. The TGF-beta superfamily contains conserved polypeptide growth factors that play important roles in different cellular...
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Characterization of Endoplasmic Reticulum Stress and Apoptosis in Macrophages Infected with Mycobacterium tuberculosis Isolates from Korea Patients

Lee JH, Lim YJ, Choi JA, Han JY, Cho SH, Oh SM, Song CH

Apoptosis is an important host defense mechanism against mycobacterial infection. Recent reports suggest that links between apoptosis and endoplasmic reticulum (ER) stress are critical for the regulation of mycobacterial survival;...
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Current Trends in Studies of Epstein-Barr Virus (EBV) Associated Gastric Carcinoma

Lee M, Ryu E, Sung GH, Shin YS, Kim JG, Kang BW, Cho H, Kang H

EBV infection has been causally associated with incidence of many carcinomas. EBV-associated gastric carcinoma (EBVaGC) has been classified as a unique gastric carcinoma subset, suggesting EBV infection is related to...
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Transcriptional Profiling of an Attenuated Salmonella Typhimurium ptsI Mutant Strain Under Low-oxygen Conditions using Microarray Analysis

Lim S, Han A, Kim D, Seo HS

Salmonella causes a wide variety of diseases ranging from mild diarrhea to severe systemic infections, such as like typhoid fever, in multiple organisms, ranging from mice to humans. A lack...
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Safety and Immunogenicity of a Recombinant Rabies Virus Strain (ERAG3G) in Korean Raccoon Dogs

Yang DK, Kim HH, Jo HY, Kim HW, Choi SS, Cho IS

A new alternative rabies bait vaccine strain named ERAG3G, which is applicable to wild animals, was developed to eliminate rabies in South Korea. In this study, the safety and immunogenicity...
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Sero-surveillance of Getah Virus among Thoroughbred Horses in Korea

Jo HY, Yang DK, Kim HH, Choi SS, Kang KS, Yang SJ, Yang YJ, Cho IS

Getah virus (GETV), which is transmitted by mosquitoes, causes lower limb edema and stiffness in horses. In this study, we investigated the sero-surveillance of GETV among Thoroughbred racehorses in Korea...
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Association between Polymorphisms in Toll-like Receptor 9 Gene and Outcomes after Ischemic Stroke

Choi JC, Lee KH, Kim YR, Ki CS

Several evidences suggested that Toll-like receptor 9 (TLR9) plays an important role in atherosclerosis and neuroprotection but the association between the TLR9 and risk for stroke or outcomes after stroke...
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The Growth Inhibition Effect on the Bacterial Vaginosis Causative Bacteria by Citric Acid and Trisodium Phosphate

Yang NW, Sihn WJ

Bacterial vaginosis (BV) is the most frequent vaginal disease being apt to relapse. The growth inhibition effect of the mixture of citric acid (CA) and trisodium phosphate (TSP) on BV...
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