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Antigen Distributions of Rotavirus and Adenovirus Detected by Enzyme Immuno Assay (EIA) from Acute Gastroenteritis Patients in Seoul

Ham H, Oh S, Jo S, Choi S

Antigen distributions of rotavirus and adenovirus were detected by enzyme immuno assay (EIA) in patients with acute gastroenteritis in Seoul from 2008 to 2012. Tested feces sample numbers from patients...
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Interplay between Intestinal Microbiota and Host Immune System

Mazmanian , Lee YK

Whether we are aware or not, diverse microorganisms are living on almost all environmentally exposed surfaces on our body without eliciting harmful immune responses. In fact, recent understanding from numerous...
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cGAS-cGAMP Signaling and Antiviral Defense

Manzoor Z, Koh YS

Cyclic guanosine monophosphate-adenosine monophosphate (cGAMP) synthase (cGAS) is a cytosolic DNA sensor that plays an important role in innate immunity. Transfection of DNA or DNA virus infection results in the...
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Human Immunodeficiency Virus Type 1 Tat-Mediated Cellular Response in Myeloid Cells

Kim NY, Kim YW

Human immunodeficiency virus type 1 (HIV-1)-infected cells respond to the infection with different outcomes depending on their cell type. The interplay of cellular and viral proteins is a key player...
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Insight into the Pathogenesis of Lyme Disease

Shin OS

Lyme disease is the most common vector-borne disease in the United States and Europe, caused by a tick-borne spirochete, Borrelia burgdorferi. Life cycle alternation between arthropod and mammals enhanced B....
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Comparisons of CTX-M-Producing Escherichia coli Isolates from Humans and Animals in South Korea

Choi MJ, Lim SK, Jung SC, Ko KS

To investigate the possibility of transmission of CTX-M-producing Escherichia coli isolates among humans and animals, we compared CTX-M-producing E. coli isolates showing the same genotype from humans and dogs in...
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Angiostatin Works as Immune Modulatory Molecules via Inhibition of Neutrophil Activation and Migration

Woo SY

Angiostatin is derived from enzymatic degradation of plasminogen and it has endogenous anti-angiogenic properties. Although tumor cells, macrophages, platelets, and neutrophils generate high amount of angiostatin, its expression is increased...
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Naturally Occurring Mutations of Hepatitis B virus and Hepatitis C Virus in Korean Chronic Patients by Distinct CD4 T Cell Responses

Kim H, Kim BJ

Hepatitis B virus (HBV) and hepatitis C virus (HCV) infections are among the most common causes of chronic liver disease worldwide. The host immune pressure against hepatitis viruses during the...
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Identification of Leptospira species of Korean Isolates using Phylogenetic Analysis of Polymerase Chain Reaction-amplified 16S rDNA and LipL32 Genes

Park KH, Choi YJ, Shin SH, Choi MK, Kim YW, Jang WJ

In this study, we selected only serologically identified 15 Leptosira interrogans isolates in the past and analyzed and identified them by using molecular method. The partial 16S rDNA and LipL32...
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HIV-1 Tat Protein Promotes Amyloid beta Generation and Tau Phosphorylation in Rat Hippocampal Slices

Lee EO, Jhang KA, An YW, Ju W, Chong YH

HIV-1 Tat protein has been implicated as a causative agent in the pathogenesis of HIV-1-associated neurocognitive disorder (HAND) and Alzheimer's disease (AD)-like pathology in HIV-1 infected patients. Here, we provide...
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Anti-inflammatory Effect of Plocamium telfairiae Extract in LPS-stimulated Bone Marrow-derived Macrophages and Dendritic Cells

Shrestha E, Kim S, Chae D, Manzoor Z, Yoo ES, Kang HK, Hyun JW, Ko MH, Koh YS

Marine algae are rich sources of various biologically active compounds with potential pharmaceutical properties. In the present study, we investigated the inhibitory effects of Plocamium telfairiae extract (PTE) on proinflammatory...
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Analysis of env Subtypes of Porcine Endogenous Retrovirus in SNU Miniature Pigs

Sa M, Park CG, Hwang ES

All xenografts from pigs impose infection risk by porcine endogenous retrovirus (PERV). The purpose of this study was to investigate the env constructs with the comparison of the ratio of...
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Antibody Response in Cattle and Guinea Pigs Inoculated with Rabies Vaccines

Yang DK, Jeong WH, Kim HH, Nah JJ, Kim JJ, Choi SS, Kim JT, Song JY

One hundred ninety-five rabies cases in cattle were identified in South Korea since 1993. As most of rabies cases have a relation to rabid Korean raccoon dogs (Nyctereutes procyonoides koreensis),...
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Evaluation of Immune Response for Vi-CRM(197) Conjugated Vaccine against Salmonella enterica serovar Typhi in Mice

Kim K, Shim J, Park S, Park B, Cho Y, Hur B, Kang SA, Choi SK, Baik Y, Hahn TW

Typhoid fever, a serious systemic infection caused by Salmonella enterica serovar Typhi, breaks out in developing countries. However, existing vaccines only induce relatively low protective effects with humoral responses and...
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Regulation of microRNA-7-5p and LRP6 by Epstein-Barr Virus-Encoded RNAs in Burkitt's Lymphoma Cell Line Akata

Son JW, Choi HY, Lee HN, Seo MK, Lee SK

Epstein-Barr virus (EBV)-encoded small non-coding RNAs (EBERs) are abundantly expressed in various EBV-associated malignancies, and play critical roles in cell proliferation, tumorigenesis, and apoptosis resistance. However, the mechanism how EBERs...
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