- Effects of Phosphodiesterase 5 Inhibition with Sildenafil on Atrial Contractile and Secretory Function
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Quan HX, Kim SY, Jin XS, Park JK, Kim SZ, Cho KW
- KMID: 2285326
- Korean J Physiol Pharmacol.
- 2006 Jun;10(3):149-154.
Selective inhibition of phosphodiesterase (PDE) 5 opened a new therapeutic approach for cardiovascular disorders. Therefore, the effect of PDE5 inhibition on the cardiac function should thoroughly be defined. The purpose... -
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- Prostaglandin E1 Increases cGMP Levels in Beating Rabbit Atria: Lack of Effects of PGE1-induced Cyclic Nucleotides on Secretory and Contractile Functions
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Jin XS, Quan HX, Kim SY, Park SH, Kim SZ, Lee HS, Cho KW
- KMID: 2285340
- Korean J Physiol Pharmacol.
- 2007 Oct;11(5):175-182.
Members of prostaglandin (PG) E-series elicit cellular effects mainly through adenylyl cyclase-cAMP signaling. The role of PGE2-induced increase in cAMP has been shown to be compartmentalized in the cardiac myocytes:... -
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