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RET Fusion Genes in Korean Non-Small Cell Lung Cancer

Yoo SS, Jin G, Jung HJ, Hong MJ, Choi JE, Jeon HS, Lee SY, Lim JO, Park JY

Recently, rearranged during transfection (RET) fusions have been identified in approximately 1% of non-small cell lung cancer (NSCLC). To know the prevalence of RET fusion genes in Korean NSCLCs, we...
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Polymorphisms in Apoptosis-Related Genes and TP53 Mutations in Non-Small Cell Lung Cancer

Bae EY, Lee EJ, Kang HG, Lee SY, Jin G, Lee WK, Choi JE, Jeon HS, Lim JO, Lee EB, Park JY

Apoptosis plays an essential role in the elimination of mutated or transformed cells from the body. Therefore, polymorphisms of apoptosis-related genes may lead to an alteration in apoptotic capacity, thereby...
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EML4-ALK Fusion Gene in Korean Non-Small Cell Lung Cancer

Jin G, Jeon HS, Lee EB, Kang HG, Yoo SS, Lee SY, Lee JH, Cha SI, Park TI, Kim CH, Jheon SH, Park JY

A fusion gene between echinoderm microtubule-associated protein-like 4 (EML4) and the anaplastic lymphoma kinase (ALK) has been identified in non-small cell lung cancers (NSCLCs). Although a few studies have evaluated...
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A Functional Polymorphism in the CHRNA3 Gene and Risk of Chronic Obstructive Pulmonary Disease in a Korean Population

Lee JY, Yoo SS, Kang HG, Jin G, Bae EY, Choi YY, Choi JE, Jeon HS, Lee J, Lee SY, Cha SI, Kim CH, Park JY

A genome-wide association study has identified the 15q25 region as being associated with the risk of chronic obstructive pulmonary disease (COPD) in Caucasians. This study intended as a confirmatory assessment...
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Gender Differences in Aggression-related Responses on EEG and ECG

Im S, Jin G, Jeong J, Yeom J, Jekal J, Lee SI, Cho JA, Lee S, Lee Y, Kim DH, Bae M, Heo J, Moon C, Lee CH

Gender differences in aggression viewed from an evolutionary and sociocultural perspective have traditionally explained why men engage in more direct and physical aggression, and women engage in more indirect and...
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TP53 Mutations in Korean Patients with Non-small Cell Lung Cancer

Lee EB, Jin G, Lee SY, Park JY, Kim MJ, Choi JE, Jeon HS, Cha SI, Cho S, Kim CH, Park TI, Jung TH, Son JW, Park JY

Although TP53 mutations have been widely studied in lung cancer, the majority of studies have focused on exons 5-8 of the gene. In addition, TP53 mutations in Korean patients with...
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Family History and Stroke Risk in China: Evidence from a Large Cohort Study

Tian T, Jin G, Yu C, Lv J, Guo Y, Bian Z, Yang L, Chen Y, Shen H, Chen Z, Hu Z, Li L, China Kadoorie Biobank Collaborative Group

BACKGROUND AND PURPOSE: Large cohort studies on relationship between family history of stroke (FHS) and stroke risk are lacking in Asians. We aimed to systematically evaluate the association of FHS...
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Significance of Low-Attenuation Cluster Analysis on Quantitative CT in the Evaluation of Chronic Obstructive Pulmonary Disease

Nambu A, Zach J, Kim SS, Jin G, Schroeder , Kim YI, Bowler R, Lynch DA

OBJECTIVE: To assess clinical feasibility of low-attenuation cluster analysis in evaluation of chronic obstructive pulmonary disease (COPD). MATERIALS AND METHODS: Subjects were 199 current and former cigarette smokers that underwent CT...
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