- Insulin signal transduction pathway
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Jhun BH, Lee MK
- KMID: 1700077
- J Korean Diabetes Assoc.
- 1993 Dec;17(4):337-345.
No abstract available. -
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- Adverse effects of farnesyltransferase inhibitors on insulin actions
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Yi SJ, Jhun BH, Kim K
- KMID: 2394597
- J Biomed Transl Res.
- 2017 Sep;18(3):113-117.
- doi: 10.12729/jbtr.2017.18.3.113
Ras activates a series of downstream effectors, including the mitogen-activated protein kinase pathway and the Rac/Rho pathway after insulin stimulation. Mutations in Ras are found in approximately 30% of all... -
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- STP-A11, an oncoprotein of Herpesvirus saimiri augments both NF-kappaB and AP-1 transcription activity through TRAF6
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Jeong S, Cho IR, An WG, Jhun BH, Lee BS, Park K, Chung YH
- KMID: 1103681
- Exp Mol Med.
- 2007 Feb;39(1):56-64.
Herpesvirus saimiri (HVS), a member of the gamma-herpesvirus family, encodes an oncoprotein called Saimiri Transforming Protein (STP) which is required for lymphoma induction in non-human primates. However, a detailed mechanism... -
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- Role of Ras/ERK-dependent pathway in the erythroid differentiation of K562 cells
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Kang CD, Do IR, Kim KW, Ahn BK, Kim SH, Chung BS, Jhun BH, Yoo MA
- KMID: 1029935
- Exp Mol Med.
- 1999 Jun;31(2):76-82.
The chronic myelogenous leukemic K562 cell line carrying Bcr-Abl tyrosine kinase is considered as pluripotent hematopoietic progenitor cells expressing markers for erythroid, granulocytic, monocytic, and megakaryocytic lineages. Here we investigated the signaling modulations... -
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- Pancreatic adenocarcinoma up-regulated factor (PAUF) enhances the expression of beta-catenin, leading to a rapid proliferation of pancreatic cells
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Cho IR, Koh SS, Min HJ, Kim SJ, Lee Y, Park EH, Ratakorn S, Jhun BH, Oh S, Johnston R, Chung YH
- KMID: 1097265
- Exp Mol Med.
- 2011 Feb;43(2):82-90.
- doi: 10.3858/emm.2011.43.2.010
It is not yet understood how the enhanced expression of pancreatic adenocarcinoma up-regulated factor (PAUF; a novel oncogene identified in our recent studies), contributes to the oncogenesis of pancreatic cells.... -
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