- Transcriptional mutagenesis by 8-oxodG in alpha-synuclein aggregation and the pathogenesis of Parkinson's disease
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Basu S, Je G, Kim YS
- KMID: 2155433
- Exp Mol Med.
- 2015 Aug;47(8):e179.
- doi: 10.1038/emm.2015.54
Parkinson's disease (PD) is an age-related progressive neurodegenerative disease associated with selective loss of dopaminergic neurons. The characteristic hallmark of the disease is intracytoplasmic proteinacious inclusion bodies called Lewy bodies,... -
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- Regulation of Αlpha-Synuclein Gene (SNCA) by Epigenetic Modifier TET1 in Parkinson Disease
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Guhathakurta S, Song MK, Basu S, Je G, Cristovao AC, Kim YS
- KMID: 2536157
- Int Neurourol J.
- 2022 Nov;26(Suppl 2):S85-93.
- doi: 10.5213/inj.2222206.103
Purpose: Deregulation of SNCA encoding α-synuclein (α-SYN) has been associated with both the familial and sporadic forms of Parkinson disease (PD). Epigenetic regulation plays a crucial role in PD. The... -
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- Polymorphism of Nitric Oxide Synthase 1 Affects the Clinical Phenotypes of Ischemic Stroke in Korean Population
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Yoo SD, Park JS, Yun DH, Kim HS, Kim SK, Kim DH, Chon J, Je G, Kim YS, Chung JH, Chung SJ, Yeo JA
- KMID: 2155172
- Ann Rehabil Med.
- 2016 Feb;40(1):102-110.
- doi: 10.5535/arm.2016.40.1.102
OBJECTIVE: To investigate whether four single nucleotide polymorphisms (SNPs) rs2293054 [Ile734Ile], rs1047735 [His902His], rs2293044 [Val1353Val], rs2682826 (3'UTR) of nitric oxide synthase 1 (NOS1) are associated with the development and clinical... -
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