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Yoo W, Jung HY, Lim S, Sung JS, Park KH, Ryu JS, Shin SW, Kim JS, Seo JH, Kim YH
KMID: 2167536
Cancer Res Treat.
2011 Jun;43(2):108-116.
PURPOSE: The genetic alteration of the janus kinases (JAKs), non-receptor tyrosine kinase, is related to the development of human cancers. However, little is known about how the sequence variation of...
Specific gene expressions of host cells by spontaneous STAT6 phosphorylation are major strategy for the survival of intracellular Toxoplasma gondii against parasiticidal events through STAT1 phosphorylation by infection provoked IFN-γ....
Oh YB, Ahn M, Lee SM, Koh HW, Lee SH, Kim SH, Park BH
KMID: 2154242
Exp Mol Med.
2013 May;45(5):e23.
Recent studies have documented that Janus-activated kinase (JAK)-signal transducer and activator of transcription (STAT) pathway can modulate the apoptotic program in a myocardial ischemia/reperfusion (I/R) model. To date, however, limited...
Persistently activated JAK/STAT3 signaling pathway plays a pivotal role in various human cancers including major carcinomas and hematologic tumors, and is implicated in cancer cell survival and proliferation. Therefore, inhibition...