- Non-canonical vs. Canonical Functions of Heme Oxygenase-1 in Cancer
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Jagadeesh ASV, Fang X, Kim SH, Guillen-Quispe YN, Zheng J, Surh YJ, Kim SJ
- KMID: 2528081
- J Cancer Prev.
- 2022 Mar;27(1):7-15.
- doi: 10.15430/JCP.2022.27.1.7
Heme oxygenase-1 (HO-1) is a critical stress-responsive enzyme that has antioxidant and anti-inflammatory functions. HO-1 catalyzes heme degradation, which gives rise to the formation of carbon monoxide (CO), biliverdin, and... -
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- Interaction between Peptidyl-prolyl Cis-trans Isomerase NIMA-interacting 1 and GTP-H-Ras: Implications for Aggressiveness of Human Mammary Epithelial Cells and Drug Resistance
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Saeidi S, Joo S, Kim SJ, Jagadeesh ASV, Surh YJ
- KMID: 2510153
- J Cancer Prev.
- 2020 Dec;25(4):234-243.
- doi: 10.15430/JCP.2020.25.4.234
Aberrant activation of Ras has been implicated in aggressiveness of breast cancer. Among Ras isoforms (H-, K-, and N-), H-Ras has been known to be primarily responsible for invasion and... -
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