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Magnolol exerts anti-asthmatic effects by regulating Janus kinase-signal transduction and activation of transcription and Notch signaling pathways and modulating Th1/Th2/Th17 cytokines in ovalbumin-sensitized asthmatic mice

Huang Q, Han L, Lv R, Ling L

Allergic asthma, is a common chronic inflammatory disease of the airway presenting with airway hyperresponsiveness and airway remodelling. T helper cells-derived cytokines are critically associated with asthma pathogenesis. Janus kinase-signal...
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Interaction of Hepatitis C Virus Core Protein with Janus Kinase Is Required for Efficient Production of Infectious Viruses

Lee C

  • KMID: 1502510
  • Biomol Ther.
  • 2013 Mar;21(2):97-106.
Chronic hepatitis C virus (HCV) infection is responsible for the development of liver cirrhosis and hepatocellular carcinoma. HCV core protein plays not only a structural role in the virion morphogenesis...
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Activation of Stat Protein in Synovial Cell in Rheumatoid Arthritis

Shim SC, Lee IH, Jung JH, Kim TH, Jun JB, Song KW, Bae SC, Yoo DH, Kim SY

  • KMID: 2202485
  • J Korean Rheum Assoc.
  • 2000 Mar;7(1):43-52.
OBJECTIVE: To characterize Stat activity in synovial tissue in rheumatoid arthritis (RA) in order to see if Stat molecule contributes to the pathogenesis of RA by regulatory expression of...
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