- Efficacy of Asenapine in Drug-resistant Psychotic Patients with Dopamine Supersensitivity Psychosis: Two Cases
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Kanahara N, Kimura H, Kinoshita T, Iyo M, Takekita Y
- KMID: 2539664
- Clin Psychopharmacol Neurosci.
- 2023 Feb;21(1):197-201.
- doi: 10.9758/cpn.2023.21.1.197
Dopamine supersensitivity psychosis (DSP) is an unstable clinical condition observed in individuals with schizophrenia who have been treated with an antipsychotic medication at a high dosage and/or for a long... -
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- Reduction of Severity of Recurrent Psychotic Episode by Sustained Treatment with Aripiprazole in a Schizophrenic Patient with Dopamine Supersensitivity: A Case Report
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Tadokoro S, Nonomura N, Kanahara N, Hashimoto , Iyo M
- KMID: 2367670
- Clin Psychopharmacol Neurosci.
- 2017 Feb;15(1):79-81.
- doi: 10.9758/cpn.2017.15.1.79
Dopamine supersensitivity psychosis (DSP) is a type of acute exacerbation of recurrent psychosis caused by long-term treatment with antipsychotics in schizophrenic patients. Although DSP is exceedingly troublesome for clinicians, effective... -
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- An Open Study of Sulforaphane-rich Broccoli Sprout Extract in Patients with Schizophrenia
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Shiina A, Kanahara N, Sasaki T, Oda Y, Hashimoto , Hasegawa T, Yoshida T, Iyo M, Hashimoto
- KMID: 2171066
- Clin Psychopharmacol Neurosci.
- 2015 Apr;13(1):62-67.
- doi: 10.9758/cpn.2015.13.1.62
OBJECTIVE: Schizophrenia is a mental disorder characterized by severe cognitive impairment. Accumulating evidence suggests a role for oxidative stress in the pathophysiology of schizophrenia. Sulforaphane (SFN) extracted from broccoli sprout... -
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- Occupancy of alpha7 Nicotinic Acetylcholine Receptors in the Brain by Tropisetron: A Positron Emission Tomography Study Using [11C]CHIBA-1001 in Healthy Human Subjects
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Ishikawa M, Sakata M, Toyohara J, Oda K, Ishii K, Wu J, Yoshida T, Iyo M, Ishiwata K, Hashimoto
- KMID: 2171255
- Clin Psychopharmacol Neurosci.
- 2011 Dec;9(3):111-116.
OBJECTIVE: Agonists of alpha7-nicotinic acetylcholine receptors (nAChRs) have been developed as potential therapeutic drugs for neuropsychiatric diseases such as schizophrenia and Alzheimer's disease. Positron emission tomography (PET) is a noninvasive... -
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