- Effects of N-Acetylcysteine on Nicotinamide Dinucleotide Phosphate Oxidase Activation and Antioxidant Status in Heart, Lung, Liver and Kidney in Streptozotocin-Induced Diabetic Rats
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Lei S, Liu Y, Liu H, Yu H, Wang H, Xia Z
- KMID: 1120195
- Yonsei Med J.
- 2012 Mar;53(2):294-303.
- doi: 10.3349/ymj.2012.53.2.294
PURPOSE: Hyperglycemia increases reactive oxygen species (ROS) and the resulting oxidative stress plays a key role in the pathogenesis of diabetic complications. Nicotinamide dinucleotide phosphate (NADPH) oxidase is one of... -
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- Oxidatvive Stress in Rat Model of Preeclampsia and Clinical Correlates
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Chang YJ, Lee WK, Kim HG
- KMID: 2285336
- Korean J Physiol Pharmacol.
- 2007 Jun;11(3):129-133.
There are growing evidences suggesting a pivotal role of oxidative stress in the pathophysiology of preeclampsia. We investigated oxidative stress in the rat model of preeclampsia, and in clinical cases.... -
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- The Effect of Repetitive Hypoxia on Production of Lipid Peroxidation in Newborn Rat Brain
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Kim IS, Suk HJ, Park JS, Park MS, Park MS
- KMID: 2144561
- J Korean Soc Neonatol.
- 2003 Nov;10(2):235-240.
PURPOSE: Among many pathophysiologic mechanisms of hypoxic-ischemic brain injury, reactive oxygen species (ROS) cause or contribute to brain damage relates to their ability to attack the fatty acid moiety of... -
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- Umbilical Cord Arterial Concentrations of Isoprostane(8-iso-PGF2alpha) in Newborn Infants
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Lee KS, Ji YH, Chang YP
- KMID: 1607029
- J Korean Pediatr Soc.
- 2003 Sep;46(9):865-870.
PURPOSE: We measured the umbilical cord arterial concentrations of isoprostane(8-iso-PGF2alpha) and intended to decide whether the umbilical cord arterial concentrations of isoprostane could be used as a useful parameter for... -
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- Efficacy of midtrimester amniotic fluid 8-isoprostane measurement in the prediction of severe preeclampsia
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Kim SR, Lee PR, Koo BS, Kim JS, Chung JY, Won HS, Kim A
- KMID: 2129002
- Korean J Obstet Gynecol.
- 2002 Oct;45(10):1785-1793.
OBJECTIVE: The objective of this study is to investigate whether the amniotic fluid 8-isoprostane levels at the time of genetic amniocentesis is a marker for severe preeclampsia. METHODS: A case-control... -
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- Changes in the Levels of Eicosanoids and Isoprostane (8-iso-PGF2alpha) in the Newborn Rat Brain after Hypoxic-Ischemic Injury
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Lee HY, Jung MK, Kim JA, Chang YP, Hyun KS, Kim HG, Hwang TJ
- KMID: 2099016
- J Korean Soc Neonatol.
- 2000 May;7(1):45-53.
PURPOSE: The changes in the levels of eicosanoids and isoprostane (8-iso-PGF2alpha) were investigated in brain tissue of 7 day-old rats after hypoxic-ischemic (HI) injury. METHODS: The 7 day-old newborn rats... -
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- Simultaneous HPLC analysis of arachidonic acid metabolites in biological samples with simple solid phase extraction
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Kim HG, Huh YN, Park KS
- KMID: 2071837
- Korean J Physiol Pharmacol.
- 1998 Dec;2(6):779-786.
A reversed-phase high-performance liquid chromatography (RP-HPLC) has been developed to analyze the metabolites of arachidonic acid based on the specificities of ultraviolet absorption of these various metabolites and is sensitive to the nanogram... -
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