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Production of Human Fab Monoclonal Antibody to Surface Protein, preS1, of Hepatitis B Virus using Antibody Phage Display Library

Kim HS, Choi IH, Kim IJ, Chung JH, Park SK

  • KMID: 1548380
  • Korean J Immunol.
  • 1997 Dec;19(4):549-558.
Human monoclonal antibodies have considerable potential in the prophylaxis and treatment of viral disease. By cloning human Ig gene segments from the B cells of volunteer into pComb3 phagemid vector,...
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Cloning, Sequencing and Expression in Escherichia coli of Herpes simple virus Type-1 Thymidine Kinase Gene

Lee HB, Kim JW, Kang H, Cha SC

  • KMID: 1551987
  • J Korean Soc Virol.
  • 1998 Sep;28(3):215-224.
Cloning, sequencing and expressing in E. coli of the thymidine kinase (TK) gene of Herpes simplex virus type-1 (HSV-1) strain F was investigated. The TK gene, located in the BamHI...
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Production of IL-15 and lts Functional Study in Mouse Splenocyte Activation

Han IS, Park JW

  • KMID: 1550738
  • Korean J Immunol.
  • 1999 Dec;21(4):297-302.
After the synthesis of IL-15 cDNA from the total RNA of mouse spleen, it was inserted into the prokaryotic expression vector, pRseta, and eukaryotic expression vector, pcDNA3.0, respectively. Subsequently, the...
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Production of Mouse Single Chain Fv Antibody to Surface Protein of Hepatitis B virus using Antibody Phage Display Library

Choi IH, Kim HS, Kim IJ, Chung JH, Park SK

  • KMID: 2001267
  • J Korean Soc Microbiol.
  • 1997 Aug;32(4):447-454.
In this study, we are to produce the single chain variable fragment (scFv) antibodies against surface protein of hepatitis B virus (HBV) using antibody phage display technique. Balb/c mice were...
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Site-Specific Mutagenesis in Human Cells by Bulky Exocyclic Amino-Substituted Guanine and Adenine Derivatives

Moon KY

  • KMID: 2127916
  • Cancer Res Treat.
  • 2004 Apr;36(2):151-156.
PURPOSE: 7-Bromomethylbenz[a]anthracene is a well- known mutagen and carcinogen. The aim of this study is to determine the mutagenic potency of its two major DNA adducts [N2-(benz[a]anthracen-7-ylmethyl)-2'-deoxyguanosine (b[a]a2G) and N6-(benz[a]anthracen-7-...
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Clinical Significance and Outcomes of Initial No Growth Peritonitis from Peritoneal Dialysis Patients: Role of Mycobacterial or Fungal Peritonitis

Lee SW, Park JY, Jeong JC, Ahn SY, Park JJ, Seo WW, Kim CH, Lee S, Hwang JH, Joo KW, Kim DK, Ahn C, Oh KH

  • KMID: 2080113
  • Korean J Nephrol.
  • 2010 Nov;29(6):742-751.
PURPOSE: Peritoneal dialysis associated peritonitis (PD peritonitis) is an important complication in maintaining. There have been only a few reports on the clinical outcome of initial no-growth peritonitis (INGP). METHODS: We...
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cDNA Cloning and Expression of Angiostatin, an Angiogenesis Inhibitor , from Human Liver Tissue mRNA

Park MJ, Hwang BG, Son YS, Yi DH, Lee SH, Hong SI

  • KMID: 2175135
  • J Korean Cancer Assoc.
  • 1999 Dec;31(6):1236-1245.
PURPOSE: Angiostatin, a 38 kDa internal fragment of plasminogen, is a potent inhibitor of angiogenesis. It blocks neovascularization and growth of primary and metastatic tumors in mice. To produce recombinant...
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