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Regulation of mammalian pyruvate dehydrogenase complex by phosphorylation: complexity of multiple phosphorylation sites and kinases

Patel MS, Korotchkina LG

  • KMID: 1457529
  • Exp Mol Med.
  • 2001 Dec;33(4):191-197.
This review summarizes the recent developments on the regulation of human pyruvate dehydrogenase complex (PDC) by site-specific phosphorylation by four kinases. Mutagenic analysis of the three phosphorylation sites of human...
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Secretion of adenylate kinase 1 is required for extracellular ATP synthesis in C2C12 myotubes

Choo HJ, Kim BW, Kwon OB, Lee CS, Choi JS, Ko YG

Extracellular ATP (exATP) has been known to be a critical ligand regulating skeletal muscle differentiation and contractibility. ExATP synthesis was greatly increased with the high level of adenylate kinase 1...
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Enhanced expression of neuronal nitric oxide synthase and phospholipase C-gamma1 in regenerating murine neuronal cells by pulsed electromagnetic field

Kim SS, Shin HJ, Eom DW, Huh JR, Woo Y, Kim H, Ryu SH, Suh PG, Kim MJ, Kim JY, Koo TW, Cho YH, Chung SM

  • KMID: 1093598
  • Exp Mol Med.
  • 2002 Mar;34(1):53-59.
Pulsed electromagnetic field (PEMF) has been shown to improve the rate of peripheral nerve regeneration. In the present study we investigated the expression of neuronal nitric oxide synthase (nNOS) and...
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Menin represses JunD transcriptional activity in protein kinase Ctheta-mediated Nur77 expression

Kim H, Lee JE, Kim BY, Cho EJ, Kim ST, Youn HD

  • KMID: 1089456
  • Exp Mol Med.
  • 2005 Oct;37(5):466-475.
TCR signaling leading to thymocyte apoptosis is mediated through the expression of the Nur77 family of orphan nuclear receptors. It has been shown that the Nur77 promoter is activated by...
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