- Bronchial Hyperresponsiveness in Workers Exposed to Isocyanates
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Choi KS, Kim KS, Choi BS, Choi JK, Lee SH, Moon YH
- KMID: 2282793
- Korean J Prev Med.
- 1996 Mar;29(1):103-112.
We studied the association of nonspecific bronchial hyperresponsiveness with general characteristics, exposure concentration, respiratory symptoms, chest x-ray findings, past histories and pulmonary function. We determined bronchial hyperresponsiveness by methacholine challenge... -
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- Inadvertent topical exposure to isocyanates caused damage to the entire eyeball
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Koh HJ, Kim SH, Kwon OW
- KMID: 754271
- Korean J Ophthalmol.
- 2000 Jun;14(1):38-40.
- doi: 10.3341/kjo.2000.14.1.38
Isocyanates are part of a group of important chemicals necessary in the production of adhesives, synthetic rubbers, and a variety of plastics. They are known to have minimal toxic effects... -
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- A Case of Chromium- and Toluene Diisocyanate-Induced Asthma
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- KMID: 2299671
- Korean J Asthma Allergy Clin Immunol.
- 2005 Sep;25(3):223-227.
There have been case reports of occupational asthma (OA) due to chromium in cement workers. Isocyanates are used in the manufacture of numerous products, such as polyurethane paints, and are... -
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- Prognostic factors in patients with reactive dye or isocyanate-induced occupational asthma after avoidance of causative agents
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Lee SF, Kim YK, Kim WK, Son JW, Cho SH, Min KU, Kim YY
- KMID: 2286057
- J Asthma Allergy Clin Immunol.
- 1999 Jun;19(3):484-491.
BACKGROUND: Although occupational asthma is defined as a reversible airway obstruction causally related to exposure in the working environment, many occupational asthmatics complain of asthmatic symptoms despite avoidance of the... -
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- Airway hyperresponsiveness among workers exposed to isocyanates at Yeocheon petrochemical plant
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Jang AS, Choi IS, Lee S, Seo JP, Yang SW, Moon JD, Lee KJ
- KMID: 2286055
- J Asthma Allergy Clin Immunol.
- 1999 Jun;19(3):468-475.
OBJECTIVE: To investigate the prevalence of airway hyperresponsiveness induced by isocyanate at one petrochemical industry complex in Yeochon, Korea. METHOD: Questionnaires, allergic skin prick test, toluene diisocyanate (TDI)-specific IgE, and... -
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- Toluene diisocyanate inhalation bronchial challenge test with a closed- circuit device
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Hong CS, Park JW, Kim CW, Kang SM, Choi YH
- KMID: 2365359
- Allergy.
- 1995 Dec;15(4):598-610.
Occupational asthma is the most common respiratory disease related to the working environments. Isocyanates, especially toluene diisoeyanate(TDI), are currently the most common cause of occupational asthma both in Korea and... -
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- Work-Related Asthma in Korea - Findings from the Korea Work-Related Asthma Surveillance (KOWAS) program, 2004-2009
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Kwon SC, Song J, Kim YK, Calvert GM
- KMID: 2260152
- Allergy Asthma Immunol Res.
- 2015 Jan;7(1):51-59.
- doi: 10.4168/aair.2015.7.1.51
PURPOSE: To determine the incidence and epidemiological characteristics of work-related asthma in Korea. METHODS: During 2004-2009, the Korea Work-Related Asthma Surveillance (KOWAS) program collected data on new cases of work-related asthma... -
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- Effects of MBL2 polymorphisms in patients with diisocyanate-induced occupational asthma
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Kim SH, Bae SJ, Palikhe S, Ye YM, Park HS
- KMID: 2070276
- Exp Mol Med.
- 2015 Apr;47(4):e157.
- doi: 10.1038/emm.2015.10
Diisocyanate (DI) is the most common cause of occupational asthma (OA) in Korea. Mannose-binding lectin (MBL) initiates the lectin complement activation pathway following oxidative stress and plays an important role... -
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- Biomarkers Predicting Isocyanate-Induced Asthma
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Palikhe NS, Kim JH, Park HS
- KMID: 2260373
- Allergy Asthma Immunol Res.
- 2011 Jan;3(1):21-26.
- doi: 10.4168/aair.2011.3.1.21
Three diisocyanates can cause occupational asthma (OA): toluene diisocyanate (TDI), 4,4 diphenylmethane diisocyanate (MDI), and 1,6-hexamethylene diisocyanate (HDI). We analyzed potential biomarkers of isocyanate-induced OA, based on investigated immunologic, genetic,... -
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- Role of vitamin D-binding protein in isocyanate-induced occupational asthma
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Kim SH, Choi GS, Nam YH, Kim JH, Hur GY, Kim SH, Park SM, Park HS
- KMID: 1383793
- Exp Mol Med.
- 2012 May;44(5):319-329.
The development of a serological marker for early diagnosis of isocyanate-induced occupational asthma (isocyanate-OA) may improve clinical outcome. Our previous proteomic study found that expression of vitamin D-binding protein (VDBP)... -
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