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Immunohistochemical localization of eight phospholipase C isozymes in pancreatic islets of the mouse

Kim SS, Jun KS, Jeong MJ, Ryu SH, Suh PG, Shin HS

  • KMID: 938881
  • Exp Mol Med.
  • 2001 Sep;33(3):164-168.
The possible involvement of phospholipase C (PLC) in the regulation of insulin secretion is not clearly understood and neither its isozymes expressed nor cellular localization in the pancreatic islets is...
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Immunohistochemical Study of the Pancreatic Endocrine Cells in the BALB/c mice: An Unique Distributional Pattern of Glucagon

Ku SK, Lee HS, Lee JH

  • KMID: 1095117
  • J Vet Sci.
  • 2002 Sep;3(3):167-173.
The regional distribution and relative frequency of insulin-, glucagon-, somatostatin- and pancreatic polypeptide (PP)-producing endocrine cells in the pancreas of BALB/c mouse were investigated by immunohistochemical method. The pancreas of...
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A mechanism of differential expression of GLUT2 in hepatocyte and pancreatic beta-cell line

Kim JW, Kim YK, Ahn YH

  • KMID: 754982
  • Exp Mol Med.
  • 1998 Mar;30(1):15-20.
DNase I footprinting assay using liver nuclear extracts revealed six protected regions between nucleotide -600 and +110 and hence named Box I-VI. Upstream promoter element (UPE), a DNA element playing crucial role...
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An immunohistochemical Study on the Pancreatic Endocrine Cells of the C57BL/6 Mouse

Ku SK, Lee HS, Lee JH

  • KMID: 1097350
  • J Vet Sci.
  • 2002 Dec;3(4):327-333.
The regional distribution and relative frequency of the pancreatic endocrine cells in the C57BL/6 mouse were studied by immunohistochemical method using four types of specific mammalian antisera against insulin, glucagon,...
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The stimulatory effect of IL-1beta on the insulin secretion of rat pancreatic islet is not related with iNOS pathway

Jeong IK, Oh SH, Chung JH, Min YK, Lee MS, Lee MK, Kim KW

  • KMID: 1093592
  • Exp Mol Med.
  • 2002 Mar;34(1):12-17.
Interleukin 1 (IL-1) is a pleiotropic cytokine with the potential to destroy pancreatic beta-cells, and thought to be involved in the pathogenesis of type I diabetes mellitus. Expression of inducible...
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Epigallocatechin gallate, a constituent of green tea, suppresses cytokine-induced pancreatic beta-cell damage

Han MK

  • KMID: 1097262
  • Exp Mol Med.
  • 2003 Apr;35(2):136-139.
Cytokines produced by immune cells infiltrating pancreatic islets have been implicated as one of the important mediators of beta-cell destruction in insulin-dependent diabetes mellitus. In this study, the protective effects...
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Inhibition of BETA2/NeuroD by Id2

Ghil SH, Jeon YJ, Suh-Kim H

  • KMID: 755209
  • Exp Mol Med.
  • 2002 Nov;34(5):367-373.
Id (Inhibitor of Differentiation) proteins belong to a family of transcriptional modulators that are characterized by a helix loop helix (HLH) region but lack the basic amino acid domain. Id...
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