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Ménière's Disease and Electrophysiology

Kim SH

Inner ear is composed of cochlea, vestibule, and endolymphatic sac which are enclosed by thin layer of epithelial cells. The enclosed space is filled with fluid named as endolymph where...
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Effects of Hydrogen Peroxide on Rabbit Corneal Bioelectric Properties

Ryu KH, Suh DJ, Oum BS

  • KMID: 1950327
  • J Korean Ophthalmol Soc.
  • 1995 Aug;36(8):1395-1406.
The rabbit cornea was studied in vitro in modified Ussing chambers to determine the effects of ion transport inhibitors and hydrogen peroxide(H2O2) on ion transport through the cornea by measuring...
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Tweety Homologs (TTYH) Freshly Join the Journey of Molecular Identification of the VRAC/VSOR Channel Pore

Okada Y

No abstract available.
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Molecular aspects of organic ion transporters in the kidney

Cha SH, Hitoshi E

  • KMID: 2285231
  • Korean J Physiol Pharmacol.
  • 2001 Apr;5(2):107-122.
A function of the kidney is elimination of a variety of xenobiotics ingested and wasted endogenous compounds from the body. Organic anion and cation transport systems play important roles to protect the...
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Uridine-5'-Triphosphate Stimulates Chloride Secretion via Cystic Fibrosis Transmembrane Conductance Regulator and Ca2+-Activated Chloride Channels in Cultured Human Middle Ear Epithelial Cells

Son EJ, Gee HY, Lee MG, Lee WS, Choi JY

BACKGROUND AND OBJECTIVES: Nucleotide binding to purinergic P2Y receptors contributes to the regulation of fluid and ion transport in the middle ear epithelial cells. Here, we investigated the regulatory mechanism...
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Expression and Distribution of the Na+ : HCO3- Cotransporter(NBC) and K+ : Cl- Cotransporter(KCC) mRNA in Human Nasal Mucosa and Nasal Polyp

Oh BH, Kwon YW, Choi JH, Shin DJ, Cho WJ, Jun HS, Kim SH, Lee HM, Lee SH

  • KMID: 2276213
  • Korean J Otolaryngol-Head Neck Surg.
  • 2004 Sep;47(9):857-862.
BACKGROUND AND OBJECTIVES: Electrolyte transport by nasal epithelia has been suggested to be important for controlling the quantity and composition of the nasal fluid and may play an important role...
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Renal Transport of Urate

Lee S, Kang KP, Kang SK

  • KMID: 2052259
  • Electrolyte Blood Press.
  • 2005 Nov;3(2):79-81.
All urate transport occurs across the renal epithelial cells of the proximal tubule. Most of the filtered urate is reabsorbed in the S1 segment of the early proximal tubule. This...
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Modulators of Ion Transport in Nasal Polyps: An in situ Measurement of Short-Circuit Current

Lee JH, Rhee CS, Kim DW, Lee CH

OBJECTIVES: To examine possible modulators of the ion transport through the apical membrane of the nasal polyps. METHODS: The study was conducted using the freshly-excised nasal polyps from the patients...
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Expression of Voltage-dependent Na+ Channels in the Albino Guinea Pig Cochlea

Lee SW, Lee SK, Cho NS, Song TH, Lee BD, Chang HS, Kang JW, Kim YJ

  • KMID: 2275619
  • Korean J Otolaryngol-Head Neck Surg.
  • 2001 Jan;44(1):15-20.
BACKGROUND AND OBJECTIVES: The endolymph produced from cochlear lateral wall regulates fluid and maintains positive endocochlear potential. Although many immunohistochemical studies of ion transport enzymes in the cochlear lateral wall...
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Variation of pH and Electrolyte in Nasal Secretum

Lee KD, Park HW, Ban YS, Choi BN, Park CY

  • KMID: 2074277
  • Korean J Otolaryngol-Head Neck Surg.
  • 1997 May;40(5):641-646.
BACKGROUND: Airway secretions partly arise from the interstitial fluid and partly from the secretory activities of respiratory epithelium and submucosal gland. The flow of water across the tracheobronchial epithelium is...
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Effect of cisplatin on Na+/H+ antiport in the OK renal epithelial cell line

Kim JY, Park YS

  • KMID: 2071526
  • Korean J Physiol Pharmacol.
  • 1998 Feb;2(1):69-76.
Cis-diamminedichloroplatinum II (cisplatin), an effective antitumor agent, induces acute renal failure by unknown mechanisms. To investigate direct toxic effects of cisplatin in the renal proximal tubular transport system, OK cell line was selected...
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Intracellular acidosis decreases the outward Na(+)-Ca2+ exchange current in guinea pig ventricular myocytes

Lee EH, Park SR, Paik KS, Suh CK

The Na(+)-Ca2+ exchange transport operating in outward mode has been suggested to cause Ca2+ entry during reperfusion or reoxygenation, exchanging extracellular Ca2+ for intracellular Na+ that has accumulated during ischemia...
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Translational Research Using Sodium/Iodide Symporter

Chung JK, Kang JH

No abstract available.
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Effect of Rhinovirus-16 Infection on the Electrophysiological Property of Cultured Tracheal Epithelial Cells

Jang YJ, Widdicombe JH

  • KMID: 1923106
  • Korean J Otolaryngol-Head Neck Surg.
  • 2003 Mar;46(3):211-215.
BACKGROUND AND OBJECTIVES: Rhinovirus infection on the airway epithelial cells results in derangement in mucociliary clearance. However, the contribution of altered ion transport across the epithelial cells in rhinovirus-induced alteration...
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pH-dependent modulation of intracellular free magnesium ions with ionselective electrodes in papillary muscle of guinea pig

Kim SJ, Cho IG, Kang HS, Kim JS

A change in pH can alter the intracellular concentration of electrolytes such as intracellular Ca2+ and Na+ ([Na+]i) that are important for the cardiac function. For the determination of the...
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Radioiodine Therapy in Differentiated Thyroid Cancer: The First Targeted Therapy in Oncology

Chung JK, Cheon GJ

Iodide uptake across the membranes of thyroid follicular cells and cancer cells occurs through an active transport process mediated by the sodium-iodide symporter (NIS). The rat and human NIS-coding genes...
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A Case of Congenital Chloride Diarrhea in Premature Infant

Yoon SK, Kim EY, Moon KR, Park SK

  • KMID: 2104628
  • J Korean Pediatr Soc.
  • 2003 Mar;46(3):308-311.
Congenital chloride diarrhea is a serious autosomal recessive disease, and defect of intestinal electrolyte absorption that involves, specifically, Cl-/HCO3- exchange in the distal part of the ileum and colon. The...
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Proteomic Evaluation of Cellular Responses of Saccharomyces cerevisiae to Formic Acid Stress

Lee SE, Park BS, Yoon JJ

  • KMID: 2312594
  • Mycobiology.
  • 2010 Dec;38(4):302-309.
Formic acid is a representative carboxylic acid that inhibits bacterial cell growth, and thus it is generally considered to constitute an obstacle to the reuse of renewable biomass. In this...
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Transcriptional and Nontranscriptional Regulation of NIS Activity and Radioiodide Transport

Jung KH, Lee KH

  • KMID: 1512503
  • Nucl Med Mol Imaging.
  • 2007 Oct;41(5):343-349.
Radioiodide transport has been extensively and successfully used in the evaluation and management of thyroid disease. The molecular characterization of the sodium/iodide symporter (NIS) and cloning of the NIS gene...
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Expression of Receptor Tyrosine Kinases in the Guinea Pig Cochlea

Lee BD, Park YJ, Chang HS, Ahn HY, Kang JW

  • KMID: 2274445
  • Korean J Otolaryngol-Head Neck Surg.
  • 1998 Aug;41(8):971-975.
BACKGROUND AND OBJECTIVES: Damage in the auditory sensory epithelia is irreversible and the resulting hearing loss is permanent in mammals. Nevertheless, mammals like birds can recover their auditory function anatomically...
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