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Interleukin-22 Attenuates Acute Pancreatitis-Associated Intestinal Mucosa Injury in Mice via STAT3 Activation

Bai J, Bai J, Yang M

Background/Aims: Interleukin-22 (IL-22) is an important cytokine maintaining homeostasis at barrier surfaces. In this study, the role of IL-22 in acute pancreatitis-associated intestinal injury was further explored. Methods: Severe acute pancreatitis...
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IL-17 and IL-17C Signaling Protects the Intestinal Epithelium against Diisopropyl Fluorophosphate Exposure in an Acute Model of Gulf War Veterans' Illnesses

Patterson KM, Vajdic TG, Martinez GJ, Feller AG, Reynolds JM

Gulf War Veterans' Illnesses (GWI) encompasses a broad range of unexplained symptomology specific to Veterans of the Persian Gulf War. Gastrointestinal (GI) distress is prominent in veterans with GWI and...
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Role of DNA Methylation in the Development and Differentiation of Intestinal Epithelial Cells and Smooth Muscle Cells

Jorgensen , Ro S

  • KMID: 2454636
  • J Neurogastroenterol Motil.
  • 2019 Jul;25(3):377-386.
  • doi: 10.5056/jnm19077
The mammalian intestine contains many different cell types but is comprised of 2 main cell types: epithelial cells and smooth muscle cells. Recent in vivo and in vitro evidence has...
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Curcumin protects against the intestinal ischemia-reperfusion injury: involvement of the tight junction protein ZO-1 and TNF-alpha related mechanism

Tian S, Guo R, Wei S, Kong Y, Wei X, Wang W, Shi X, Jiang H

Present study aimed to investigate the eff ect of curcumin-pretreatment on intestinal I/R injury and on intestinal mucosa barrier. Thirty Wistar rats were randomly divided into: sham, I/R, and curcumin...
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Berberine Prevents Intestinal Mucosal Barrier Damage During Early Phase of Sepsis in Rat through the Toll-Like Receptors Signaling Pathway

Li GX, Wang XM, Jiang T, Gong JF, Niu LY, Li N

Our previous study has shown berberine prevents damage to the intestinal mucosal barrier during early phase of sepsis in rat through mechanisms independent of the NOD-like receptors signaling pathway. In...
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Effect of Vitamin E Supplementation on Intestinal Barrier Function in Rats Exposed to High Altitude Hypoxia Environment

Xu C, Sun R, Qiao X, Xu C, Shang X, Niu W, Chao Y

The study was conducted to investigate the role of vitamin E in the high altitude hypoxia-induced damage to the intestinal barrier in rats. Sprague-Dawley rats were divided into control (Control),...
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The Role of Cellular Senescence in the Gastrointestinal Mucosa

Penfield J, Anderson M, Lutzke L, Wang KK

Cellular senescence is a biologically irreversible state of cell-growth arrest that occurs following either a replicative or an oncogenic stimulus. This phenomenon occurs as a response to the presence of...
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A review on gastric leptin: the exocrine secretion of a gastric hormone

Cammisotto P, Bendayan M

A major advance in the understanding of the regulation of food intake has been the discovery of the adipokine leptin a hormone secreted by the adipose tissue. After crossing the...
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Inflammatory Bowel Diseases and Enteric Microbiota

Kim JM

Intestinal mucosal layers are colonized by a complex microbiota that provides beneficial effects under normal physiological conditions, but is capable of contributing to chronic inflammatory disease such as inflammatory bowel...
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Small Intestinal Mucosa Associated Lymphoid Tissue (MALT) Lymphoma in a Child Presenting with Recurrent Intussusception: A Case Report

Seo HE, Lee JH, Park TI, Lee KS

Mucosa associated lymphoid tissue (MALT) lymphoma is a malignant B cell lymphoma that develops from MALT. The stomach is the most common site of MALT lymphomas but be found anywhere...
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Epigallocatechin-3-gallate Suppresses Galactose-alpha1,4-galactose-beta1,4-glucose Ceramide Expression in TNF-alpha Stimulated Human Intestinal Epithelial Cells Through Inhibition of MAPKs and NF-kappa B

Moon DO, Choi SR, Lee CM, Kim GY, Lee HJ, Park YM

Intestinal epithelial cells (IECs) have been known to produce galactose-alpha1,4-galactose-beta1,4-glucose ceramide (Gb3) that play an important role in the mucosal immune response. The regulation of Gb3 is important to prevent...
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Activated Mast Cells Infiltrate in Close Proximity to Enteric Nerves in Diarrhea-predominant Irritable Bowel Syndrome

Park CH, Joo YE, Choi SK, Rew JS, Kim SJ, Lee MC

Mast cells (MC) may be one factor influencing the response of visceral afferent nerves to mechanical and chemical stimuli. The aim of this study was to evaluate the degree of...
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Protective Effect of Capsaicin on the Ischemia-Reperfusion Injury of the Intestine in Rats

Kim WY, Lim KS, Park HS

  • KMID: 2194086
  • J Korean Soc Emerg Med.
  • 2002 Jun;13(2):155-162.
PURPOSE: Capsaicin, a major ingredient of hot peppers, has a stimulatory effect on the neurons. Ingested capscaicin causes pain and even damages the mucosa with a large dose. On the...
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Glutamine on the Luminal Microbial Environment After Massive Small Bowel Resection

Choi SH, Lee S, Lee MD

To evaluate the oral glutamine (GLN) on the luminal microbes and bacterial translocation (BT) in short bowel, 45 Wistar rats were utilized in three groups; A (control), and B...
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Quantitative Analysis of Small Intestinal Mucosa Using Morphometry in Cow's Milk-Sensitive Enteropathy

Hwang JB, Kim YJ

  • KMID: 2072554
  • Korean J Pediatr Gastroenterol Nutr.
  • 1998 Sep;1(1):45-55.
PURPOSE: To make objective standards of small intestinal mucosal changes in cow's milk-sensitive enteropathy (CMSE) we analyzed histological changes of endoscopic duodenal mucosa biopsy specimens from normal children and patients...
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Role of Helocobacter pylori in Gastro-duodenl Mucosal Lesions in Patients with End-stage Renal Disease

Cho GJ, Lee SB, Lee YI, Park SM, Seong EY, Kwak IS, Rha HY

  • KMID: 2307389
  • Korean J Nephrol.
  • 1997 Sep;16(3):531-536.
Helocobacter pylori(Hp) is thought to play an important role in the pathogenesis of active gastritis and other upper gastrointestinal mucosal lesions. Although upper gastrointestinal mucosal lesion have been one of...
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Enteric Cyst in the Tongue

Shim JY, Kim HG

  • KMID: 2037302
  • Korean J Pathol.
  • 1997 Nov;31(11):1237-1239.
A case of enteric cyst in the anterior two-thirds of the tongue is reported. The patient, a 42 day-old female infant, presented with a protruding tongue mass since birth. Under...
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The Effect of Intraluminal Oxygen Insufflation on the Oxygenation of Gut Mucosa in Hemorrhaged Cats

Lee YM, Park PH, Kim JU, Jo SS

BACKGROUND: This study was purposed to study the therapeutic value of intraluminal oxygen insufflation on the oxygenation of gut mucosa in a feline model subjected to a hemorrhagic shock followed...
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Histological Changes in Ileal Reservoir Mucosa after Long-term Exposure to Urine

Kong YJ, Shim BS, Park YY

  • KMID: 2114934
  • Korean J Urol.
  • 1994 Sep;35(9):944-948.
Mucosal biopsies were obtained for histological and electron microscopical studies from 7 patients with ileal urinary conduit. Shortly after construction of the reservoir there was a reduction in villous height...
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