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Diagnosis of interstitial lung diseases: from Averill A. Liebow to artificial intelligence

Yi ES, Wawryko P, Ryu JH

Histopathologic criteria of usual interstitial pneumonia (UIP)/idiopathic pulmonary fibrosis (IPF) were defined over the years and endorsed by leading organizations decades after Dr. Averill A. Liebow first coined the term...
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Clinical characteristics of juvenile systemic sclerosis in Korea: 31-year single-center study

Jeong JE, Kim SH

Objective: To evaluate the clinical and laboratory characteristics, therapeutic drugs, and prognosis of juvenile systemic sclerosis (JSSc) at a single center in Korea. Methods: This study was a retrospective analysis of...
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Radiologic approach and progressive exploration of connective tissue disease-related interstitial lung disease: meeting the curiosity of rheumatologists

Jeon H, Nam BD, Yoon CH, Kim HS

Interstitial lung disease (ILD) is often observed in connective tissue diseases (CTDs), frequently in rheumatoid arthritis, systemic sclerosis, primary Sjögren’s syndrome, and inflammatory myositis. Early detection of ILDs secondary to...
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Diagnostic Approaches for Idiopathic Pulmonary Fibrosis

Lee JH, Song JW

Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, fibrosing interstitial pneumonia with a very poor prognosis. Accurate diagnosis of IPF is essential for good outcomes but remains a major medical...
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Cystic Degeneration of Uterine Fibroid Mimicking Heterotopic Pregnancy with In terstitial Pregnancy: A Case Report

Moon H, Hong SM, Lee YJ, Lee J

Heterotopic pregnancy with interstitial pregnancy is a rare condition with fatal consequences if diagnosis is delayed. Hence, previous reports have focused on criteria and tools that can expedite obstetricians’ diagnosis....
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Promising Therapeutic Effects of Embryonic Stem Cells-Origin Mesenchymal Stem Cells in Experimental Pulmonary Fibrosis Models: Immunomodulatory and Anti-Apoptotic Mechanisms

Lee H, Jeong OY, Park HJ, Lee SL, Bok Ey, Kim M, Suh YS, Cheon YH, Kim HO, Kim S, Chun SH, Park JM, Lee YJ, Lee SI

Interstitial lung disease (ILD) involves persistent inflammation and fibrosis, leading to respiratory failure and even death. Adult tissue-derived mesenchymal stem cells (MSCs) show potential in ILD therapeutics but obtaining an...
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Application and Interpretation of High-Resolution Computed Tomography for the Diagnosis of Interstitial Lung Disease (ILD): ILD Protocol

Han Jy, Lee JH

Interstitial lung disease (ILD) encompasses a heterogeneous group of over 200 diffuse parenchymal lung diseases. Accurate diagnosis of ILD is essential for appropriate treatment but can be challenging to achieve....
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A Case of Interstitial Pneumonia in Patients with Psoriasis Treated with Methotrexate

Lee SS, Ha DL, Kim JY, Jang YH, Lee WJ, Lee SJ, Park KD

  • KMID: 2548462
  • Korean J Dermatol.
  • 2023 Nov;61(9):571-574.
Methotrexate (MTX) is commonly employed in the management of chronic inflammatory skin diseases. We report the case of a 73-year-old man who presented with a persistent cough lasting for 1...
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General Overview of Artificial Intelligence for Interstitial Cystitis in Urology

Cho Y, Park JM, Youn S

Our understanding of interstitial cystitis/bladder pain syndrome (IC/BPS) has evolved over time. The diagnosis of IC/BPS is primarily based on symptoms such as urgency, frequency, and bladder or pelvic pain....
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Nailfold capillaroscopy findings of interstitial pneumonia with autoimmune features

Lee SH, Min HK, Kim SH, Kim YW, Yoo KH, Kim HJ, Kim IA, Kim HR

Background/Aims: We evaluated nailfold capillaroscopy (NFC) of interstitial pneumonia with autoimmune features (IPAF) and compared it with that of patients with connective tissue disease-interstitial lung disease (CTD-ILD) and idiopathic interstitial...
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Successful Trastuzumab-Deruxtecan Rechallenge After Interstitial Lung Disease: A Case Report

Weger VAd, Schutte T, Konings IR, van Oordt CWMvdH

Trastuzumab deruxtecan (T-DXd) is used to treat human epidermal growth factor receptor 2-positive advanced breast cancer. Interstitial lung disease (ILD) is a severe adverse event associated with T-DXd. Current guidelines...
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Overview of aristolochic acid nephropathy: an update

Zhou Q, Jiang L, Su T, Liu G, Yang L

Aristolochic acid nephropathy (AAN) is a rapidly progressive renal interstitial fibrosis caused by medical or environmental exposure to aristolochic acid (AA). Since the outbreak of AAN in Belgium was reported...
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An Incidentally Discovered Primary Hepatic Gastrointestinal Stromal Tumor Treated by Surgical Resection and Adjuvant Imatinib Therapy: A Case Report

Park S, Han DH, Park YN, Rhee H

Gastrointestinal stromal tumors (GISTs) are rare mesenchymal tumors derived from precursors of the interstitial cells of Cajal that commonly arise from the stomach or small intestine. These tumors usually contain...
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Generative Adversarial Network-Based Image Conversion Among Different Computed Tomography Protocols and Vendors: Effects on Accuracy and Variability in Quantifying Regional Disease Patterns of Interstitial Lung Disease

Hwang HJ, Kim H, Seo JB, Ye JC, Oh G, Lee SM, Jang R, Yun J, Kim N, Park HJ, Lee HY, Yoon SH, Shin KE, Lee JW, Kwon W, Sun JS, You S, Chung MH, Gil BM, Lim JK, Lee Y, Hong SJ, Choi YW

Objective: To assess whether computed tomography (CT) conversion across different scan parameters and manufacturers using a routable generative adversarial network (RouteGAN) can improve the accuracy and variability in quantifying interstitial...
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An Optogenetics-based Approach to Regulate Colonic Contractions by Modulating the Activity of the Interstitial Cells of Cajal in Mice

Zhao S, Tong W

  • KMID: 2544721
  • J Neurogastroenterol Motil.
  • 2023 Jul;29(3):388-399.
  • doi: 10.5056/jnm22181
Background/Aims The interstitial cells of Cajal (ICC) are pacemaker cells in the gastrointestinal (GI) tract. We examined whether the activity of ICC could be stimulated to control colonic contractions. An optogenetics-based...
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Intravesical Bladder Treatment and Deep Learning Applications to Improve Irritative Voiding Symptoms Caused by Interstitial Cystitis: A Literature Review

Cho Y, Youn S

Our comprehension of interstitial cystitis/painful bladder syndrome (IC/PBS) has evolved over time. The term painful bladder syndrome, preferred by the International Continence Society, is characterized as “a syndrome marked by...
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Phase I/II prospective clinical trial for the hybrid of intracavitary and interstitial brachytherapy for locally advanced uterine cervical cancer

Murakami N, Watanabe M, Uno T, Sekii S, Tsujino K, Kasamatsu T, Machitori Y, Aoshika T, Kato S, Hirowatari H, Kaneyasu Y, Nakagawa T, Ikushima H, Ando K, Murata M, Yoshida K, Yoshioka H, Murata K, Ohno T, Okonogi N, Saito AI, Ichikawa M, Okuda T, Tsuchida K, Sakurai H, Yoshimura R, Yoshioka Y, Yorozu A, Kunitake N, Okamoto H, Inaba K, Kato T, Igaki H, Itami J

Objective The purposes of this trial were to demonstrate the feasibility and effectiveness of the hybrid of intracavitary and interstitial brachytherapy (HBT) for locally advanced cervical cancer patients in the phase...
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Transcriptome and Proteome Profiling of Primary Human Gastric Interstitial Cells of Cajal Predicts Pacemaker Networks

Foong D, Mikhael M, Zhou J, Zarrouk A, Liu X, Schröder J, Polo JM, Ho V, O’Connor MD

  • KMID: 2541576
  • J Neurogastroenterol Motil.
  • 2023 Apr;29(2):238-249.
  • doi: 10.5056/jnm22078
Background/Aims Interstitial cells of Cajal (ICC) are specialized gastrointestinal (GI) pacemaker cells required for normal GI motility. Dysfunctions in ICC have been reported in patients with GI motility disorders, such as...
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COVID-19 Vaccine-Associated Pneumonitis in the Republic of Korea: A Nationwide Multicenter Survey

Yoo H, Kim SY, Park MS, Jeong SH, Park SW, Lee HL, Lee HK, Yang SH, Jegal Y, Yoo JW, Lee J, Kang HK, Choi SM, Park J, Kim YW, Song JW, Park JH, Choi WI, Choi HS, Park C, Park JW, Chung MP

Background: Recent reports have suggested that pneumonitis is a rare complication following vaccination against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, its clinical features and outcomes are not well known....
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The Efficacy and Safety of a Human Perirenal Adipose TissueDerived Stromal Vascular Fraction in an Interstitial Cystitis Rat Model

Ha JY, Lee EH, Chun SY, Lee JN, Ha YS, Chung JW, Yoon BH, Jeon M, Kim HT, Kwon TG, Yoo ES, Kim BS

BACKGROUND: Interstitial cystitis (IC) is a chronic and intractable disease that can severely deteriorate patients’ quality of life. Recently, stem cell therapy has been introduced as a promising alternative treatment...
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