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Editorial for ‘Lower Urinary Tract Symptoms: Clinical and Translational Science’

Birder LA

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Corrigendum: Transfer Learning for Effective Urolithiasis Detection

Choi HS, Kim JS, Whangbo TK, Kim KH

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Detrusor Overactivity After Partial Bladder Outlet Obstruction Is Associated With High Urinary Adenosine Triphosphate Levels in Female Wistar Rats

Vale L, Cruz F, Charrua A

Purpose: Bladder outlet obstruction (BOO) commonly causes detrusor overactivity (DO). In this study, a post hoc analysis of previous obtained data, we investigate if DO occurring in initial phases of...
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The Ketone Bridge Between the Heart and the Bladder: How Fast Should We Go?

Faria-Costa G, Oliveira J, Vilas-Boas I, Campelo I, Silva EA, Brás-Silva C, Silva SM, Antunes-Lopes T, Charrua A

Metabolic syndrome (MS) is associated with both cardiovascular and bladder dysfunction. Insulin resistance (IR) and central obesity, in particular, are the main risk factors. In these patients, vicious pathological cycles...
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Adreno-Muscarinic Synergy of Contractile Responses From Human Hyperplastic Prostate

Blake-James BT, Chakrabarty B, Fry CH

Purpose: Adreno-muscarinic synergy, a supra-additional contractile response to simultaneous application of α-adrenoreceptor and muscarinic receptor agonists, is a feature of several lower urinary tract regions that have dual sympathetic and...
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Quantification of Aging-Related Decreases in Sensory Innervation of the Bladder Trigone in Rats

Rijk MMd, Peter S, Wolf-Johnston A, Heesakkers J, Koeveringe GAv, Birder LA

Purpose: The prevalence of lower urinary tract symptoms (LUTS), characterized by problems regarding storage and/or voiding of urine, is known to significantly increase with age. Effective communication between the lower...
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Pathophysiology of Overactive Bladder and Pharmacologic Treatments Including β3-Adrenoceptor Agonists -Basic Research Perspectives-

Kwon J, Kim DY, Cho KJ, Hashimoto M, Matsuoka K, Kamijo T, Wang Z, Karnup S, Robertson AM, Tyagi P, Yoshimura N

Overactive bladder (OAB) is a symptom-based syndrome defined by urinary urgency, frequency, and nocturia with or without urge incontinence. The causative pathology is diverse; including bladder outlet obstruction (BOO), bladder...
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Application of the Sleep C.A.L.M. Tool for Assessing Nocturia in a Large Nationally Representative Cohort

Boroda JU, Leon BD, Khosla L, Chobufo MD, Rahman SN, Lazar JM, Weiss JP, Monaghan TF

Purpose: Nocturia significantly impacts patients’ quality of life but remains insufficiently evaluated and treated. The “Sleep C.A.L.M.” system categorizes the factors thought to collectively reflect most underlying causes of nocturia...
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