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Expected Next-Generation Drugs

Kim KH

No abstract available.
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Expected Next-Generation Drugs Under Development in Relation to Voiding Symptoms

Chung KJ, Chung BI

New drug development is a high-risk venture, but if successful, will bring great revenues to those willing to accept the risk. In the field of urology, in particular for lower...
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Sociodemographic Factors Related to Lower Urinary Tract Symptoms in Men: A Korean Community Health Survey

Jo JK, Kim KS, Nam JW, Choi BY, Moon HS

PURPOSE: This study estimated the prevalence of lower urinary tract symptoms (LUTS) in Korean men and the conditions for being diagnosed with or treated for LUTS/benign prostatic hyperplasia (BPH). METHODS: We...
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Urethral Closure Pressure at Stress: A Predictive Measure for the Diagnosis and Severity of Urinary Incontinence in Women

Pizzoferrato AC, Fauconnier A, Fritel X, Bader G, Dompeyre P

PURPOSE: Maintaining urinary continence at stress requires a competent urethral sphincter and good suburethral support. Sphincter competence is estimated by measuring the maximal urethral closure pressure at rest. We aimed...
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Extracellular Vesicles as a Source of Urological Biomarkers: Lessons Learned From Advances and Challenges in Clinical Applications to Major Diseases

Choi JY, Kim S, Kwak HB, Park DH, Park JH, Ryu JS, Park CS, Kang JH

Extracellular vesicles (EVs) not only eliminate unwanted molecular components, but also carry molecular cargo essential for specific intercellular communication mechanisms. As the molecular characteristics and biogenetical mechanisms of heterogeneous EVs...
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Effects of Acute Sacral Neuromodulation at Different Frequencies on Bladder Overactivity in Pigs

Li X, Liao L, Chen G, Wang Z, Deng H

PURPOSE: We investigated the effects of different stimulation frequencies on the inhibition of bladder overactivity by sacral neuromodulation (SNM) in pigs. METHODS: Implant-driven stimulators were used to stimulate the S3 spinal...
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A Study of Clinical Predictors Associated With Intrinsic Sphincter Deficiency in Women With Stress Urinary Incontinence

Park KK, Kim SD, Huh JS, Kim YJ

PURPOSE: Recently, intrinsic sphincter deficiency (ISD) has been identified as one important factor in the outcome of stress urinary incontinence (SUI) related surgery. Clinical factors that can predict ISD are...
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Long-term Outcomes of Augmentation Enterocystoplasty in Patients With End-Stage Bladder Diseases: A Single-Institute Experience Involving 102 Patients

Wu SY, Jiang YH, Kuo HC

PURPOSE: Augmentation enterocystoplasty (AE) has been shown to improve clinical symptoms in patients with end-stage bladder disease (ESBD). Herein, we report the long-term outcomes of a series of patients with...
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Assessing the Readjustable Sling Procedure (Remeex System) for Female Stress Urinary Incontinence With Detrusor Underactivity

Ko KJ, Suh YS, Sung HH, Ryu GH, Lee M, Lee KS

PURPOSE: Many surgeons worry about postoperative voiding problems in patients with stress urinary incontinence (SUI) and detrusor underactivity (DU). This study hypothesized that adjusting the tension after surgery would benefit...
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The Risk of Upper Urinary Tract Involvement in Patients With Ketamine-Associated Uropathy

Yee CH, Teoh JY, Lai PT, Leung VY, Chu WC, Lee WM, Tam YH, Ng CF

PURPOSE: The aims of this study were to investigate the prevalence of upper tract involvement in ketamine-associated uropathy, and to determine the predictors of hydronephrosis in patients with a history...
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Targeting Moderate and Severe Male Stress Urinary Incontinence With Adjustable Male Slings and the Perineal Artificial Urinary Sphincter: Focus on Perioperative Complications and Device Explantations

Kretschmer A, Hüsch T, Thomsen F, Kronlachner D, Obaje A, Anding R, Pottek T, Rose A, Olianas R, Friedl A, Hübner W, Homberg R, Pfitzenmaier J, Queissert , Naumann CM, Wotzka C, Hofmann T, Seiler R, Haferkamp , Bauer RM, Debates On Male Incontinence (DOMINO)-Project

PURPOSE: To analyze perioperative complications and postoperative explantation rates for selected readjustable male sling systems and the perineal single-cuff artificial urinary sphincter (AUS) in a large, contemporary, multi-institutional patient cohort. METHODS:...
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