- The Role of Lysophosphatidic Acid in Adult Stem Cells
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Lee D, Kim YH, Kim JH
- KMID: 2504331
- Int J Stem Cells.
- 2020 Jul;13(2):182-191.
- doi: 10.15283/ijsc20035
Stem cells are undifferentiated multipotent precursor cells that are capable both of perpetuating themselves as stem cells (self-renewal) and of undergoing differentiation into one or more specialized types of cells.... -
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- Regenerative Therapy for Osteoarthritis: A Perspective
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Im GI, Kim TK
- KMID: 2504330
- Int J Stem Cells.
- 2020 Jul;13(2):177-181.
- doi: 10.15283/ijsc20069
Osteoarthritis (OA) is the most common type of arthritis and causes a significant deterioration in patients’ quality of life. The high prevalence of OA as well as the current lack... -
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- Effect of Conditioned Medium from Human Umbilical Cord-Derived Mesenchymal Stromal Cells on Rejuvenation of Nucleus Pulposus Derived Stem/Progenitor Cells from Degenerated Intervertebral Disc
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Zeng X, Lin J, Wu H, Yu J, Tu M, Cheang LH, Zhang J
- KMID: 2504338
- Int J Stem Cells.
- 2020 Jul;13(2):257-267.
- doi: 10.15283/ijsc20027
Background and Objectives: Mesenchymal stromal cells (MSCs)-based treatment for degeneration of intervertebral disc (IVD) has been proposed recently. We here addressed whether MSC secreted factors can rejuvenate nucleus pulposus- derived... -
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- Adipose Tissue-Derived Stem Cells from Type 2 Diabetics Reveal Conservative Alterations in Multidimensional Characteristics
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Wang L, Zhang L, Liang X, Zou J, Liu N, Liu T, Wang G, Ding X, Liu Y, Zhang B, Liang R, Wang S
- KMID: 2504339
- Int J Stem Cells.
- 2020 Jul;13(2):268-278.
- doi: 10.15283/ijsc20028
Background and Objectives: Adipose tissue-derived mesenchymal stem cells (ASCs) are recognized as an advantaged source for the prevention and treatment of diverse diseases including type 2 diabetes mellitus (T2DM). However,... -
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- Intratracheal Transplantation of Amnion-Derived Mesenchymal Stem Cells Ameliorates Hyperoxia-Induced Neonatal Hyperoxic Lung Injury via Aminoacyl-Peptide Hydrolase
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Li Z, Gong X, Li D, Yang X, Shi Q, Ju X
- KMID: 2504335
- Int J Stem Cells.
- 2020 Jul;13(2):221-236.
- doi: 10.15283/ijsc19110
Background and Objectives: Bronchopulmonary dysplasia (BPD) has major effects in premature infants. Although previous literature has indicated that mesenchymal stem cells (MSCs) can alleviate lung pathology in BPD newborns and... -
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- Overexpression of p21 Has Inhibitory Effect on Human Hematopoiesis by Blocking Generation of CD43＋ Cells via Cell-Cycle Regulation
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Zeng J, Zhang H, Liu Y, Sun W, Yi D, Zhu L, Zhang Y, Pan X, Chen Y, Zhou Y, Bian G, Lai M, Zhou Q, Liu J, Chen B, Ma F
- KMID: 2504333
- Int J Stem Cells.
- 2020 Jul;13(2):202-211.
- doi: 10.15283/ijsc20033
Background and Objectives: p21, an important member of the Cip/Kip family, is involved in inhibitory effects of RUNX1b overexpression during the early stage of human hematopoiesis. Methods and Results: We established... -
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- Effect of Cell Labeling on the Function of Human Pluripotent Stem Cell-Derived Cardiomyocytes
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Choi SW, Cho YW, Kim JG, Kim YJ, Kim E, Chung HM, Kang SW
- KMID: 2504341
- Int J Stem Cells.
- 2020 Jul;13(2):287-294.
- doi: 10.15283/ijsc19138
Cell labeling technologies are required to monitor the fate of transplanted cells in vivo and to select target cells for the observation of certain changes in vitro. Human induced pluripotent... -
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- The Distinct Role of Tcfs and Lef1 in the Self-Renewal or Differentiation of Mouse Embryonic Stem Cells
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Kim S, Kim H, Tan A, Song Y, Lee H, Ying QL, Jho Eh
- KMID: 2504332
- Int J Stem Cells.
- 2020 Jul;13(2):192-201.
- doi: 10.15283/ijsc20044
Background and Objectives: Tcfs and Lef1 are DNA-binding transcriptional factors in the canonical Wnt signaling pathway. In the absence of β-catenin, Tcfs and Lef1 generally act as transcriptional repressors with... -
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- Proliferation, Differentiation and Immunoregulatory Capacities of Brown and White Adipose-Derived Stem Cells from Young and Aged Mice
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Yang YM, Dong XH, Ma WC, Guan LH, Wang YH, Huang XH, Chen JF, Zhao X, Yang SM, Jiang XX, Wen N
- KMID: 2504337
- Int J Stem Cells.
- 2020 Jul;13(2):246-256.
- doi: 10.15283/ijsc20019
Background and Objectives: Adipose tissue is a source of mesenchymal stem cells, which have the potential to differentiate into various types of cells. Adipose-derived stem cells (ADSCs) are now recognized... -
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- Human Amniotic Epithelial Cells Affect the Functions of Neutrophils
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Alipour R, Motedayyen H, Sereshki N, Rafiee M, Alsahebfosul F, Pourazar A
- KMID: 2504334
- Int J Stem Cells.
- 2020 Jul;13(2):212-220.
- doi: 10.15283/ijsc19155
Background and Objectives: As a stem cell group, Human amniotic epithelial cells (HAECs) have numerous advantages over their embryonic and adult counterparts for therapeutic utility. They are closer to clinical... -
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- SOCS1 Regulates the Immunomodulatory Roles of MSCs on B Cells
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Zhang L, Qu YN, Zhang HY, Wu ZY, Li ZL, Guo WB, Wang QB, Fang NZ, Jiang XX
- KMID: 2504336
- Int J Stem Cells.
- 2020 Jul;13(2):237-245.
- doi: 10.15283/ijsc20001
Background and Objectives: The effective use of MSCs for the treatment of some B cell-mediated immune diseases is quite limited. The main reason is that the immunomodulatory effects of mesenchymal... -
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- Long-Term Expansion of Functional Human Pluripotent Stem Cell-Derived Hepatic Organoids
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Mun SJ, Hong YH, Ahn HS, Ryu JS, Chung KS, Son MJ
- KMID: 2504340
- Int J Stem Cells.
- 2020 Jul;13(2):279-286.
- doi: 10.15283/ijsc20060
A human cell-based liver model capable of long-term expansion and mature hepatic function is a fundamental requirement for pre-clinical drug development. We previously established self-renewing and functionally mature human pluripotent... -
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