- Improvement of Cell Cycle Lifespan and Genetic Damage Susceptibility of Human Mesenchymal Stem Cells by Hypoxic Priming
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Lee CW, Kang D, Kim AK, Kim DY, Kim DI
- KMID: 2413501
- Int J Stem Cells.
- 2018 Jun;11(1):61-67.
- doi: 10.15283/ijsc17054
Hypoxic culture is widely recognized as a method to efficiently expand human mesenchymal stem cells (MSCs) without loss of stem cell properties. However, the molecular basis of how hypoxia priming... -
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- The Role of Microenvironment in Preserving the Potency of Adult Porcine Pulmonary Valve Stem Cells In Vitro
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Chalajour , Siyahian A, Hanley FL
- KMID: 2413508
- Int J Stem Cells.
- 2018 Jun;11(1):121-130.
- doi: 10.15283/ijsc18020
BACKGROUND AND OBJECTIVE: The potency of tissue resident stem cells is regulated primarily by inputs from the local microenvironment. Isolation of stem cells through enzymatic digestion of tissue may affect... -
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- Enhancement of Replication and Differentiation Potential of Human Bone Marrow Stem Cells by Nicotinamide Treatment
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Ok JS, Song SB, Hwang ES
- KMID: 2413497
- Int J Stem Cells.
- 2018 Jun;11(1):13-25.
- doi: 10.15283/ijsc18033
BACKGROUND AND OBJECTIVES: Therapies using mesenchymal stem cells (MSCs) generally require substantial expansion of cell populations. However, the replicative life span of MSCs is limited and their multipotency declines over... -
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- Human Embryonic Stem Cell Derived from Early Stage Fertilized Ovum: Non Immunogenic and Universal, Neuronal and Non-neuronal Cell Lines
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Shroff G, Srivastav , Shroff R
- KMID: 2413506
- Int J Stem Cells.
- 2018 Jun;11(1):105-110.
- doi: 10.15283/ijsc17064
BACKGROUND: Human embryonic stem cells (hESCs) have the potential to treat various human disorders currently labeled as incurable and/or terminal illness. However, the fear that the patients' immune system would... -
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- Optimal Xeno-free Culture Condition for Clinical Grade Stem Cells from Human Exfoliated Deciduous Teeth
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Tangjit N, Dechkunakorn S, Anuwongnukroh N, Khaneungthong A, Sritanaudomchai H
- KMID: 2413505
- Int J Stem Cells.
- 2018 Jun;11(1):96-104.
- doi: 10.15283/ijsc17049
BACKGROUND AND OBJECTIVES: Stem cells from human exfoliated deciduous teeth (SHED) are a promising clinical resource for various tissue defects, including lumbar spondylosis, neural compression, and cleft palate. Use of... -
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- Large-scale Isolation, Expansion and Characterization of Human Amniotic Epithelial Cells
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Gottipamula S, Sridhar KN
- KMID: 2413504
- Int J Stem Cells.
- 2018 Jun;11(1):87-95.
- doi: 10.15283/ijsc18001
BACKGROUND AND OBJECTIVES: The human Amniotic epithelial cells (AME) derived from amniotic membrane of placenta have been considered as the potential fetal stem cell source with minimal or no ethical... -
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- The Effect of Umbilical Cord-derived Mesenchymal Stem Cell Transplantation in a Patient with Cerebral Palsy: A Case Report
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Okur SC, Erdoğan S, Demir CS, Günel G, Karaöz E
- KMID: 2413510
- Int J Stem Cells.
- 2018 Jun;11(1):141-147.
- doi: 10.15283/ijsc17077
BACKGROUND: Cerebral Palsy (CP) is the most common motor disability reason of childhood that occurs secondarily to non-progressive damage in the brain whose development is still ongoing. METHODS: 6-year-old dystonic-spastic male... -
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- PD-L1 Expression on Circulating CD34+ Hematopoietic Stem Cells Closely Correlated with T-cell Apoptosis in Chronic Hepatitis C Infected Patients
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Abdellatif H, Shiha G
- KMID: 2413503
- Int J Stem Cells.
- 2018 Jun;11(1):78-86.
- doi: 10.15283/ijsc17047
BACKGROUND AND OBJECTIVES: Lack of understanding of the interplay between hematopoietic stem cells (HSCs) and the immune system has severely hampered stem cell research. Programmed death-1 (PD-L1) has been reported... -
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- Local Mesenchymal Stem Cell Therapy in Experimentally Induced Colitis in the Rat
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de la Portilla F, Yuste Y, Pereira S, Olano C, Maestre MV, Padillo FJ
- KMID: 2413499
- Int J Stem Cells.
- 2018 Jun;11(1):39-47.
- doi: 10.15283/ijsc17074
BACKGROUND: Multipotent mesenchymal stem cells (MSCs) have been used in inflammatory bowel diseases because of their immunomodulatory and regenerative properties. We investigated their local use in an experimental model of... -
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- Therapeutic Efficacy of Mesenchymal Stem Cells and Mesenchymal Stem Cells-derived Neural Progenitors in Experimental Autoimmune Encephalomyelitis
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Nasri F, Mohtasebi , Hashemi E, Zarrabi M, Gholijani , Sarvestani EK
- KMID: 2413502
- Int J Stem Cells.
- 2018 Jun;11(1):68-77.
- doi: 10.15283/ijsc17052
BACKGROUND AND OBJECTIVES: The goal of treatment for MS is to reduce the inflammation and induce the regeneration of degenerated axons. Considering the anti-inflammatory and regenerative capacity of mesenchymal stem... -
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- The Bromodomain Inhibitor JQ1 Enhances the Responses to All-trans Retinoic Acid in HL-60 and MV4-11 Leukemia Cells
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Kang C, Kim CY, Kim HS, Park SP, Chung HM
- KMID: 2413509
- Int J Stem Cells.
- 2018 Jun;11(1):131-140.
- doi: 10.15283/ijsc18021
All-trans retinoic acid (ATRA) is a highly effective treatment for acute promyelocytic leukemia (APL), a cytogenetically distinct subtype of acute myeloid leukemia (AML). However, ATRA-based treatment is not effective in... -
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- CD73, CD90, CD105 and Cadherin-11 RT-PCR Screening for Mesenchymal Stem Cells from Cryopreserved Human Cord Tissue
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Pham H, Tonai R, Wu M, Birtolo C, Chen M
- KMID: 2413498
- Int J Stem Cells.
- 2018 Jun;11(1):26-38.
- doi: 10.15283/ijsc17015
BACKGROUND AND OBJECTIVES: Mesenchymal stem cells (MSCs) are self-renewing, non-specialized cells used clinically in tissue regeneration and sourced from bone marrow, peripheral blood, umbilical cord blood and umbilical cord tissue... -
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- TGF-β induces Smad2 Phosphorylation, ARE Induction, and Trophoblast Differentiation
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Albers RE, Selesniemi K, Natale DR, Brown TL
- KMID: 2413507
- Int J Stem Cells.
- 2018 Jun;11(1):111-120.
- doi: 10.15283/ijsc17069
BACKGROUND: Transforming growth factor beta (TGF-β) signaling has been shown to control a large number of critical cellular actions such as cell death, differentiation, and development and has been implicated... -
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- Transcriptional Profiling of Mesenchymal Stem Cells Identifies Distinct Neuroimmune Pathways Altered by CNS Disease
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Sargent A, Shano G, Karl M, Garrison E, Miller C, Miller RH
- KMID: 2413500
- Int J Stem Cells.
- 2018 Jun;11(1):48-60.
- doi: 10.15283/ijsc17062
BACKGROUND AND OBJECTIVES: Bone marrow mesenchymal stem cells (BM-MSCs) are an attractive cell based therapy in the treatment of CNS demyelinating diseases such as multiple sclerosis (MS). Preclinical studies demonstrate... -
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- Mesenchymal Stem Cell Therapy for Ischemic Heart Disease: Systematic Review and Meta-analysis
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Jeong H, Yim HW, Park HJ, Cho Y, Hong H, Kim NJ, Oh IH
- KMID: 2413496
- Int J Stem Cells.
- 2018 Jun;11(1):1-12.
- doi: 10.15283/ijsc17061
BACKGROUND AND OBJECTIVES: Mesenchymal stem cells (MSC) have emerged as breakthrough treatments for myocardial infarction. However, the efficacy of MSC remains unclear. The aim of the study was to evaluate... -
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