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Cancer Stem Cells in Brain Tumors and Their Lineage Hierarchy

Kong DS

  • KMID: 1426152
  • Int J Stem Cells.
  • 2012 May;5(1):12-15.
Despite recent advances in the development of novel targeted chemotherapies, the prognosis of malignant glioma remains dismal. The chemo-resistance of this tumor is attributed to tumor heterogeneity. To explain this...
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Delivering Factors for Reprogramming a Somatic Cell to Pluripotency

Um SH

  • KMID: 1426151
  • Int J Stem Cells.
  • 2012 May;5(1):6-11.
An adult cell originates from stem cell. The stem cell is usually categorized into three species including an embryonic stem cell (ESc), an adult stem cell, and an induced stem...
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Engineering Biomaterials for Feeder-Free Maintenance of Human Pluripotent Stem Cells

Yang K, Lee J, Cho SW

  • KMID: 1426150
  • Int J Stem Cells.
  • 2012 May;5(1):1-5.
Human pluripotent stem cells (hPSCs) are capable of differentiating into any type of somatic cell, a characteristic that imparts significant therapeutic potential. Human embryonic stem cells and induced pluripotent stem...
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Evolution of Energy Metabolism, Stem Cells and Cancer Stem Cells: How the Warburg and Barker Hypotheses Might Be Linked

Trosko JE, Kang KS

  • KMID: 1426156
  • Int J Stem Cells.
  • 2012 May;5(1):39-56.
The evolutionary transition from single cells to the metazoan forced the appearance of adult stem cells and a hypoxic niche, when oxygenation of the environment forced the appearance of oxidative...
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Clinical Response of 277 Patients with Spinal Cord Injury to Stem Cell Therapy in Iraq

Hammadi AA, Marino A, Farhan S

  • KMID: 1426160
  • Int J Stem Cells.
  • 2012 May;5(1):76-78.
BACKGROUND AND OBJECTIVES: Spinal cord injury is a common neurological problem secondary to car accidents, war injuries and other causes, it may lead to varying degrees of neurological disablement, and...
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Treatment of Spinal Muscolar Atrophy with Intrathecal Mesenchymal Cells

Andolina M

  • KMID: 1426159
  • Int J Stem Cells.
  • 2012 May;5(1):73-75.
BACKGROUND AND OBJECTIVES: SMA1 is a genetic disease that leads to a progressive apoptosis of the second motoneuron and then to a complete paralysis. There are reports of efficacy of...
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The Role of PEC Progenitors in ADPKD Progression

Lodi D, Ligabue G, Lupo V, Cavazzini

  • KMID: 1426158
  • Int J Stem Cells.
  • 2012 May;5(1):65-72.
BACKGROUND AND OBJECTIVES: Autosomal dominant polycystic kidney disease is a pathology mainly characterized by the progressive development and enlargement of cysts in each kidneys. Such as many adult epithelial tissue,...
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Stimulation of Chondrogenic Differentiation of Mesenchymal Stem Cells

Yu DA, Han J, Kim BS

  • KMID: 1426153
  • Int J Stem Cells.
  • 2012 May;5(1):16-22.
The methods for cartilage repair have been studied so far, yet many of them seem to have limitations due to the low regenerative capacity of articular cartilage. Mesenchymal stem cell...
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Enactment of a Law for Governmental Support of the Use of Cord Blood, and Ethical Issues

Lee YH, Chung Y

  • KMID: 1426162
  • Int J Stem Cells.
  • 2012 May;5(1):84-87.
In Korea, cord blood banking projects have been developed since 1996, and the 1st successful cord blood transplant was performed in 1998. Recently, "Cord Blood Management and Research Act" was...
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Effect of Stem Cell Therapy on Induced Diabetic Keratopathy in Albino Rat

Zickri MB, Ahmad NA, El Maadawi ZM, Mohamady Y, Metwally H

  • KMID: 1426157
  • Int J Stem Cells.
  • 2012 May;5(1):57-64.
BACKGROUND AND OBJECTIVES: Type 2 diabetes mellitus (DM) is a prevalent disorder. Diabetic keratopathy is a well-known ocular complication secondary to type 2 DM. Topical insulin application did not affect...
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In vivo Tracking of Human Neural Stem Cells Following Transplantation into a Rodent Model of Ischemic Stroke

Chang DJ, Moon H, Lee YH, Lee N, Lee HJ, Jeon I, Lee H, Hwang TS, Oh SH, Shin DA, Kim SU, Hong KS, Song J

  • KMID: 1426161
  • Int J Stem Cells.
  • 2012 May;5(1):79-83.
BACKGROUND AND OBJECTIVES: Ischemic stroke caused by middle cerebral artery occlusion (MCAo) is the major type of stroke, but there are currently very limited options for cure. It has been...
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Long-term Angiogenesis Efficacy Using a Heparin-Conjugated Fibrin (HCF) Delivery System with HBM-MSCs

Kim AK, Kim MH, Kim BS, Kim DI

  • KMID: 1426154
  • Int J Stem Cells.
  • 2012 May;5(1):23-30.
BACKGROUND AND OBJECTIVES: Heparin-conjugated fibrin (HCF) is suitable for the release and localization of bFGF. We analyzed the effects of a bFGF delivery system using HCF with human bone marrow-derived...
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The Levels of Pro-Inflammatory Factors Are Significantly Decreased in Cerebral Palsy Patients Following an Allogeneic Umbilical Cord Blood Cell Transplant

Bae SH, Lee HS, Kang MS, Strupp BJ, Chopp M, Moon J

  • KMID: 1426155
  • Int J Stem Cells.
  • 2012 May;5(1):31-38.
BACKGROUND AND OBJECTIVES: The transplantation of human umbilical cord blood cells (hUCBCs) has been shown to attenuate the unregulated activation of microglia in a rat model of cerebral palsy (CP)....
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