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Oral symptom manifestations in patients with COVID-19: gustatory and saliva secretion dysfunctions and pathogenetic hypotheses

Kim J, Kim JH

Coronavirus disease 2019 (COVID-19) is a highly contagious illness caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). This disease is characterized by a wide spectrum of symptoms, ranging from...
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Oral squamous carcinoma cells stimulated by Porphyromonas gingivalis-derived lipopolysaccharide induce osteoclastogenesis through a paracrine mechanism

Keum BR, Heo SC, Kim HJ

Periodontal disease (PD) is strongly linked to increased risk of oral squamous cell carcinoma (OSCC); however, the specific mechanism through which the development of PD and OSCC is simultaneously promoted...
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Nicotinamide as a therapeutic agent for bone diseases

Yoon H, Kim WJ, Cho YD, Ryoo HM

Nicotinamide (NAM), a water-soluble derivative of vitamin B3, has emerged as a potential therapeutic agent for bonerelated disorders. In particular, it promotes bone metabolism and alleviates delayed tooth eruptions associated...
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Decline in sestrin 2 expression during aging shifts mesenchymal stem cell differentiation from osteogenic to adipogenic lineage

Kim DY, Park HJ, Baek JH

Sestrin 2 (SESN2) is a member of the sestrin family of stress-induced proteins that negatively regulate agingassociated biological processes. This study aims to investigate the role of SESN2 in regulating...
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