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Implications of specific gene expression patterns in enamel knot in tooth development

Kim TY, Neupane S, Aryal YP, Lee ES, Kim JY, Suh JY, Lee Y, Sohn WJ, An SY, Ha JH, An CH, Kim JY

Enamel knot (EK)—a signaling center—refers to a transient morphological structure comprising epithelial tissue. EK is believed to regulate tooth development in early organogenesis without its own cellular alterations, including proliferation...
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Inhibitory effect of Chaenomelis Fructus ethanol extract on receptor activator of nuclear factor-kappa B ligand-mediated osteoclastogenesis

Park GH, Gu DR, Lee SH

The fruit of Chaenomeles sinensis (Thouin) Koehne (Chaenomelis Fructus) known as “Mo-Gua” in Korea has been commonly used in traditional medicine to treat inflammatory diseases, such as sore throat. However,...
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Inhibition of cell growth and induction of apoptosis by bilobalide in FaDu human pharyngeal squamous cell carcinoma

Jeong KI, Kim SG, Go DS, Kim DK

Bilobalide isolated from the leaves of Ginkgo biloba has several pharmacological activities such as neuroprotective, anti-inflammatory, and anticonvulsant. However, the effect of bilobalide on cancer has not been clearly established....
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Malignant transformation of oral lichen planus and related genetic factors

Hwang EC, Choi SY, Kim JH

Oral lichen planus (OLP) is a chronic inflammatory disease observed in approximately 0.5–2.2% of the population, and it is recognized as a premalignant lesion that can progress into oral squamous...
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