- Anti-inflammatory effects of IL-4 and IL-10 on Human Polymorphonuclear Leukocytes
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Lee SW, Hong YS, Chun CM, Moon JD, Kim SJ, Jung IC, Yoon YH, Lee BA, Moon SW, Choi SH, Moon CK
- KMID: 2157586
- J Korean Med Sci.
- 2002 Feb;17(1):7-14.
- doi: 10.3346/jkms.2002.17.1.7
Inflammatory responses are strictly regulated by coordination of pro-inflammatory and anti-inflammatory mediators. Interleukin-4 (IL-4) and interleukin-10 (IL-10) have typically the biologic anti-inflammatory effects on monocytes, but uncertain effects on polymorphonuclear... -
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- IL-4 inhibits proliferation of renal carcinoma cells by increasing the expression of p21WAF1 and IRF-1
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Yu SJ, Kim HS, Cho SW, Sohn J
- KMID: 1094082
- Exp Mol Med.
- 2004 Aug;36(4):372-379.
Interleukin (IL)-4 inhibits proliferation of several human cancer cell lines in vitro. Although IL-4 is known to regulate proliferation of lymphocytes by modulating p27KIP1 expression, the mechanism involved in the... -
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