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Associations between Single Nucleotide Polymorphisms of High Mobility Group Box 1 Protein and Clinical Outcomes in Korean Sepsis Patients

Lee K, Chang Y, Song K, Park YY, Huh JW, Hong SB, Lim CM, Koh Y

PURPOSE: High mobility group box 1 (HMGB1) plays a central role in the pathogenesis of sepsis and multiple organ dysfunction syndromes. We investigated the associations of a single nucleotide polymorphism...
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Is Whole Exome Sequencing Clinically Practical in the Management of Pediatric Crohn's Disease?

Oh SH, Baek J, Kim KM, Lee EJ, Jung Y, Lee YJ, Jin HS, Ye BD, Yang SK, Lee JK, Seo EJ, Lim HT, Lee I, Song K

BACKGROUND/AIMS: The aim of this study was to identify the profile of rare variants associated with Crohn's disease (CD) using whole exome sequencing (WES) analysis of Korean children with CD...
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