- Human beta-defensin 2 is induced by interleukin-1b in the cornealepithelial cells
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Shin JS, Kim CW, Kwon YS, Kim JC
- KMID: 1097101
- Exp Mol Med.
- 2004 Jun;36(3):204-210.
Mammalian epithelia produce the various antimicrobial peptides against the bacterial or viral infection, thereby acting as the active immune modulators in the innate immunity. In this study, we examined the... -
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- Interleukin-1beta stimulates matrix metalloproteinase-2 expression via a prostaglandin E2-dependent mechanism in human chondrocytes
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Choi YA, Lee DJ, Lim HK, Jeong JH, Sonn JK, Kang SS, Baek SH
- KMID: 1097104
- Exp Mol Med.
- 2004 Jun;36(3):226-232.
IL-1beta is known promote cyclooxygenase-2 (COX- 2) and matrix metalloproteinase-2 (MMP-2) expression. This study focuses on the characterization of the signaling cascade associated with IL-1beta-induced matrix metalloproteinase-2 (MMP- 2) regulation... -
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- The stimulatory effect of IL-1beta on the insulin secretion of rat pancreatic islet is not related with iNOS pathway
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Jeong IK, Oh SH, Chung JH, Min YK, Lee MS, Lee MK, Kim KW
- KMID: 1093592
- Exp Mol Med.
- 2002 Mar;34(1):12-17.
Interleukin 1 (IL-1) is a pleiotropic cytokine with the potential to destroy pancreatic beta-cells, and thought to be involved in the pathogenesis of type I diabetes mellitus. Expression of inducible... -
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