- IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model
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Kim YS, Choi SJ, Choi JP, Jeon SG, Oh SY, Lee BJ, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK
- KMID: 1104380
- Exp Mol Med.
- 2010 Aug;42(8):533-546.
- doi: 10.3858/emm.2010.42.8.054
IL-4 and IL-13 are closely related cytokines that are produced by Th2 cells. However, IL-4 and IL-13 have different effects on the development of asthma phenotypes. Here, we evaluated downstream... -
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