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A long-term subacute sclerosing panencephalitis survivor treated with intraventricular interferon-alpha for 13 years

Kwak M, Yeh HR, Yum MS, Kim HJ, You SJ, Ko TS

Subacute sclerosing panencephalitis (SSPE) is a rare, progressive, and fatal central nervous system disorder resulting from persistent measles virus infection. Long-term data are scarce, with a maximum follow-up period of...
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Four Consecutive Recurrent Abortions in Patient with Essential Thrombocythemia

Seo HG, Park HN, Jeon HJ, Kim YS

Essential thrombocythemia (ET) is characterized by most cases in which platelet counts exceed 1 million/µL. ET is usually no symptoms during non-pregnancy, but arterial and venous thrombosis and hemorrhage may...
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Comparison of High Dose Interferon-α2b Immunotherapy and Dacarbazine Chemotherapy as Postoperative Treatment of Malignant Melanoma

Kim SH, Chung SH

PURPOSE: Immunotherapy of malignant melanoma using Interferon-α2b increases the adaptive immune system activity remaining after surgical resection of the tumor to prevent recurrence, and enhance survival. We will compare the...
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The assessment of hepatocellular carcinoma risk in patients with chronic hepatitis B under antiviral therapy

Varbobitis I, Papatheodoridis GV

Hepatocellular carcinoma (HCC) is a primary concern for patients with chronic hepatitis B (CHB). Antiviral therapy has been reasonably the focus of interest for HCC prevention, with most studies reporting...
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Resolution of Type 2 Diabetes Mellitus Following Interferon-alpha Therapy for Chronic Hepatitis C

Park HS, Kim YJ, Moon SY, Woo JY, Choi JK, Kim KU, Park JR, Son HY, Kim DM

Hepatitis C virus (HCV) mainly affects the liver, but several tissues outside the liver have also been reported to be involved. It has been hypothesized that diabetes could be one...
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Primary Anorectal Malignant Melanoma Treated With Endoscopic Mucosal Resection

Park JH, Lee JR, Yoon HS, Jung TY, Lee EJ, Lim JG, Ko SY, Wang JH, Lee JD, Kim HY

Anorectal melanoma is a rare neoplasm that accounts for less than 1-4% of anorectal malignant tumors. The main therapeutic modality for anorectal melanoma is surgical treatment, with abdominoperineal resection or...
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A Study of a Patient with Hypereosinophilic Syndrome Presenting with Generalized Cutaneous Blisters

Lee HY, Kim JK, Lee JY, Kim MK, Hahn YS, Yoon TY

  • KMID: 2246327
  • Korean J Dermatol.
  • 2014 Jul;52(7):486-489.
Hypereosinophilic syndrome is a multisystem disorder with unexplained persistent eosinophilia and marked preference for systemic organ involvement. More than half of all patients have cutaneous involvement, usually presenting as angioedema,...
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Azidothymidine and recombinant human interferon-alpha therapy in a cat with feline immunodeficiency virus

Jang HJ, Ho YK, Kang MH, Kim SG, Park WJ, Choi IS, Kim DY, Park HM

  • KMID: 1709212
  • J Biomed Res.
  • 2014 Jun;15(2):96-99.
A 7-year-old, spayed female, domestic short hair cat showed signs of a 2-week history of chronic anorexia, depression, and severe weight loss. Upon physical examination, pyrexia, mild gingivitis, and pale...
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Cryptococcal meningitis in a patient with chronic hepatitis C treated with pegylated-interferon and ribavirin

Lee TH, Lee KO, Kim YS, Kim SM, Huh KC, Choi YW, Kang YW

Various adverse events have been reported during combination therapy with pegylated (PEG)-interferon-alpha and ribavirin, although opportunistic infections, especially cryptococcal meningitis, are very rare. A 61-year-old woman complained of headaches and...
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Interferon-alpha inhibits airway eosinophila and hyperresponsiveness in an animal asthma model

Kikkawa Y, Sugiyama K, Obara K, Hirata H, Fukushima , Toda M, Fukuda T

BACKGROUND: Asthma is characterized by a chronic inflammatory process involving high numbers of inflammatory cells and mediators which have multiple inflammatory effects on the airway. Interferon (IFN)-alpha, which is used...
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A Case of Hypereosinophilic Syndrome Presenting With Multiorgan Infarctions Associated With Disseminated Intravascular Coagulation

Park SM, Park JW, Kim SM, Koo EH, Lee JY, Lee CS, Choi DC, Lee BJ

Thromboembolism is one of the most critical complications of hypereosinophilic syndrome (HES). We report here a case of multi-organ infarctions related to HES. A 23-year-old woman was referred to our...
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Pegylated Interferon-Associated Severe Retinopathy in a Patient with Chronic Hepatitis

Kang HY, Shin MC

This paper reports a case of pegylated interferon-associated retinopathy in a patient with chronic hepatitis C. A 32-year-old female with chronic hepatitis C undergoing pegylated interferon and ribavirin combination therapy...
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Completion of Chronic Hepatitis C Virus Treatment in Interferon-Induced Major Depressive Disorder with Psychotic Features

Park SH

  • KMID: 2316153
  • Psychiatry Investig.
  • 2011 Dec;8(4):381-383.
Interferon (IFN)-associated psychiatric disorders can be managed without interruption to hepatitis C virus (HCV) treatment. The limited number of cases in the literature reporting psychotic depression as an adverse drug...
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Clinical features of infantile hepatic hemangioendothelioma

Kim EH, Koh KN, Park M, Kim BE, Im HJ, Seo JJ

PURPOSE: Infantile hepatic hemangioendothelioma (IHHE) is the most common type of hepatic vascular tumor in infancy. We conducted this study to review our clinical experience of patients with IHHE and...
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Vogt-Koyanagi-Harada disease occurring during pegylated interferon-alpha2b and ribavirin combination therapy for chronic hepatitis C

Lim JH, Lee YN, Kim YS, Kim SG, Jeong SW, Jang JY, Kim HS, Lee SH, Park TK

Vogt-Koyanagi-Harada (VKH) disease is a multisystem syndrome characterized by ocular (uveitis and retinal detachment), neurological (headache, tinnitus, and meningitis), and integumentary (vitiligo, alopecia, and poliosis) involvement. Although the pathogenesis of...
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Perivascular epithelioid cell tumor (PEComa) of the ascending colon: the implication of IFN-alpha2b treatment

Park SJ, Han DK, Baek HJ, Chung SY, Nam JH, Kook H, Hwang TJ

A 7-year-old boy presented with hematochezia and abdominal pain. A 3.7-cm-sized mass was identified in the ascending colon by abdominal computed tomography and colonoscopy. The patient underwent surgical resection. Pathological...
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Toll-like receptor 9 expression and interferon-alpha secretion upon CpG-ODN stimulation in allergic subjects

Han MY, Jee HM, Kim HY, Lee CA, Cho HJ, Hwang SG, Kim KE

PURPOSE: The aim of this study is to explore the effect of the Toll-like receptor 9 (TLR9) expressed in plasmacytoid dendritic cells (pDCs) that respond to antigen to Th2 immune...
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Giant Acral Melanoma on the Left Thumb of a Korean Patient

Kim JH, Jeong SY, Shin JB, Ro KW, Seo SH, Son SW, Kim IH

The acral regions of the limbs of Asians are predisposed to develop malignant melanoma, but giant-sized acral melanoma has not been previously reported in the Asian population. Giant-sized melanoma implies...
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Efficacy of Long-term Interferon-alpha Therapy in Adult Patients with Recurrent Respiratory Papillomatosis

Nam HS, Koh WJ, Suh GY, Chung MP, Kwon OJ, Kim H

  • KMID: 2319100
  • Tuberc Respir Dis.
  • 2008 Nov;65(5):390-395.
BACKGROUND: Since the early 1980s, interferon-alpha (IFN-alpha) has been used as adjuvant therapy in pediatric patients with recurrent respiratory papillomatosis (RRP). However, its efficacy in adults needs to be validated....
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A Congenital Giant Hepatic Hemangioendothelioma Treated with Interferon-alpha and Complete Tumor Resection

Cho MA, Yu JE, Park MS, Park JE, Hong J, Kim YB

  • KMID: 1477472
  • J Korean Soc Neonatol.
  • 2008 Nov;15(2):183-189.
Infantile hepatic hemangioendotheliomas (IHHEs) are benign vascular tumors, but can be associated with the life-threatening complications, such as congestive heart failure, disseminated intravascular coagulation, and massive bleeding. Various therapeutic options...
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