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Role of VEGF in Kidney Development, Microvascular Maintenance and Pathophysiology of Renal Disease

Kim BS, Goligorsky MS

  • KMID: 1106138
  • Korean J Intern Med.
  • 2003 Jun;18(2):65-75.
Vascular endothelial growth factor, VEGF, is essential for endothelial cell differentiation (vasculogenesis) and for the sprouting of new capillaries from preexisting vessels (angiogenesis). In addition, there is strong evidence that...
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Transplantation of betacellulin-transduced islets improves glucose intolerance in diabetic mice

Song MY, Bae UJ, Jang KY, Park BH

Type 1 diabetes is an autoimmune disease caused by permanent destruction of insulin-producing pancreatic beta cells and requires lifelong exogenous insulin therapy. Recently, islet transplantation has been developed, and although...
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Monocrotaline-induced pulmonary hypertension correlates with upregulation of connective tissue growth factor expression in the lung

Lee YS, Byun J, Kim JA, Lee JS, Kim KL, Suh YL, Kim JM, Jang HS, Lee JY, Shin IS, Suh W, Jeon ES, Kim DK

  • KMID: 1033098
  • Exp Mol Med.
  • 2005 Feb;37(1):27-35.
Pulmonary hypertension (PH) is characterized by structural and functional changes in the lung including proliferation of vascular smooth muscle cells (VSMCs) and excessive collagen synthesis. Although connective tissue growth factor...
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