- Development of thymic lymphomas in mice disrupted of Brca2 allele in the thymus
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Park PG, Lee H
- KMID: 756336
- Exp Mol Med.
- 2008 Jun;40(3):339-344.
- doi: 10.3858/emm.2008.40.3.339
Germ-line mutations in BRCA2 predispose to early-onset cancer. Homozygous mutant mouse, which has Brca2 truncated in exon 11 exhibit paradoxic occurrence of growth retardation and development of thymic lymphomas. However,... -
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- Optimization of Streptomyces bacteriophage phiC31 integrase system to prevent post integrative gene silencing in pulmonary type II cells
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Aneja MK, Geiger J, Imker R, Uzgun S, Kormann M, Hasenpusch G, Maucksch C, Rudolph C
- KMID: 1099868
- Exp Mol Med.
- 2009 Dec;41(12):919-934.
- doi: 10.3858/emm.2009.41.12.098
phiC31 integrase has emerged as a potent tool for achieving long-term gene expression in different tissues. The present study aimed at optimizing elements of phiC31 integrase system for alveolar type... -
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