- The Tumor Suppressor Function of PTEN/MMAC1 through the Regulation of IGFs and IGFBPs
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Yi HK, Hwang DJ, Kim SY, Lee DY, Hwang PH
- KMID: 1875814
- Korean J Pediatr.
- 2004 Aug;47(8):884-891.
PURPOSE: PTEN/MMAC1, a novel tumor suppressor gene, is mutated in a variety of advanced and metastatic cancers. It acts as a phosphatase, and thereby, regulates the PI-3 kinase/Akt pathway. In... -
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- Insulin-like Growth Factor Binding Proteins(IGFBPs) Profiles in CordSera of Appropriate-for gestational Age, Small-for-gestational Age,Large-for-gestational Age Infant and Preterm Infant
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Kim JG, Ku SY, Kim SH, Choi YM, Shin CJ, Moon SY, Lee JY
- KMID: 2271653
- Korean J Obstet Gynecol.
- 1997 Mar;40(3):581-590.
The insulin-like growth factor(IGF) system consists of IGFs, their receptor and binding proteins(IGFBPs). The IGFs are important growth factors in the regulation of fetal growth. Since IGFBPs control IGF actions,... -
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- Study of the Mechanism for the Growth Inhibitory Effects of Conjugated Linoleic Acid on Caco-2 Colon Cancer Cells
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Oh EJ, Oh YS, Lee HS, Park HS, Yoon JH
- KMID: 2269651
- Korean J Nutr.
- 2003 Apr;36(3):270-279.
Conjugated linoleic acid (CLA) is a group of positional and geometric isomers of linoleic acid (LA) and exhibits anticarcinogenic activity in a variety of animal models. We have previously observed... -
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- Antepartal insulin-like growth factor concentrations indicating differences in the metabolic adaptive capacity of dairy cows
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Piechotta , Holzhausen L, Araujo MG, Heppelmann M, Sipka A, Pfarrer C, Schuberth , Bollwein H
- KMID: 2155617
- J Vet Sci.
- 2014 Sep;15(3):343-352.
- doi: 10.4142/jvs.2014.15.3.343
Cows with different Insulin-like Growth Factor-I (IGF-I) concentrations showed comparable expression levels of hepatic growth hormone receptor (GHR). Suppressor of cytokine signaling 2 (SOCS2), could be responsible for additional inhibition... -
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- Increased Activity of Insulin-like Growth Factor binding Protein-4 Protease in H-mole Patients
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Seo WS, Byun DW, Mok JO, Yoon JS, Kim YJ, Park HK, Kim CH, Kim SJ, Suh KI, Yoo MH, Lee HH, Rah SK
- KMID: 2200522
- J Korean Soc Endocrinol.
- 2004 Aug;19(4):346-357.
BACKGROUND: Hydatidiform mole (H-mole) is characterized by the neoplastic proliferation of trophoblasts. Only 1~10% of patients with partial H-mole will develop a trophoblastic tumor, but 18~29% of those with complete... -
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- Growth impairment of primary chondrocyte cells by serum of rats with chronic renal failure
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Mak RH, Chang SL, Pak YK
- KMID: 1097106
- Exp Mol Med.
- 2004 Jun;36(3):243-250.
Insulin-like growth factor (IGF)/IGF binding protein (IGFBP) abnormalities may be important in the pathogenesis of growth failure in chronic renal failure (CRF). We induced experimental CRF by 5/6 nephrectomy in... -
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