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Ibrutinib reduces neutrophil infiltration, preserves neural tissue and enhances locomotor recovery in mouse contusion model of spinal cord injury

Torabi S, Anjamrooz SH, Zeraatpisheh Z, Aligholi H, Azari H

Following acute spinal cord injury (SCI), excessive recruitment of neutrophils can result in inflammation, neural tissue loss and exacerbation of neurological outcomes. Ibrutinib is a bruton’s tyrosine kinase inhibitor in...
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Secondary hypoxic ischemia alters neurobehavioral outcomes, neuroinflammation, and oxidative stress in mice exposed to controlled cortical impact

Oh SK, Park HJ, Yu GG, Jeong SH, Lee SW, Kim H

Objective Hypoxic ischemia (HI) is a secondary insult that can cause fatal neurologic outcomes after traumatic brain injury (TBI), ranging from mild cognitive deficits to persistent vegetative states. We here...
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External validation and comparison of the Pediatric Emergency Care Applied Research Network and Canadian Assessment of Tomography for Childhood Head Injury 2 clinical decision rules in children with minor blunt head trauma

Kwon BS, Song HJ, Lee JH

Objective Among the pediatric population with minor head trauma, it is difficult to determine an indication for the usage of brain computerized tomography (CT). Our study aims to compare the...
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Experiences of Emergency Surgical Treatment for a COVID-19 Patient with Severe Traumatic Brain Injury at a Regional Trauma Center: A Case Report

Yun JH

Various medical scenarios have arisen with the prolonged coronavirus disease 2019 (COVID-19) pandemic. In particular, the increasing number of asymptomatic COVID-19 patients has prompted reports of emergency surgical experiences with...
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Visual Disturbance Caused by a Nail Gun-Induced Penetrating Brain Injury

Ye JB, Sul YH, Kim SH, Lee JY, Lee JS, Kim HR, Yoon SY, Choi JH

Penetrating brain injury caused by a nail gun is an uncommon clinical scenario reported in the literature. A 36-year-old male presented with a nail that had penetrated through the occipital...
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Management of Traumatic Pancreatic Injuries: Evaluation of 7 Years of Experience at a Single Regional Trauma Center

Lee MA, Lee SH, Choi KK, Park Y, Lee GJ, Yu B

Purpose Traumatic pancreatic injuries are rare, but their diagnosis and management are challenging. The aim of this study was to evaluate and report our experiences with the management of pancreatic injuries. Methods We...
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Endophthalmitis and Retinal Detachment after Ocular Injury by Animal Inoculation Needle

Kwon L, Cho YW, Seo SW, Kim SJ, Chung IY, Yoo WS

Purpose: To report a case of endophthalmitis and retinal detachment after injury caused by an animal inoculation needle. Case summary: A 39-year-old man received an injury to his left eye...
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Epidemiological Characteristics of Bicycle-related Injuries with the Emergence of the COVID-19

Ko BS, Cho SH, Noh DY, Kim JG

Purpose: Following the outbreak and global spread of the coronavirus disease 2019 (COVID-19), an increasing number of people have turned to cycling. This study aims to investigate the epidemiology of...
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A Prognostic Factor for Prolonged Mechanical Ventilator-Dependent Respiratory Failure after Cervical Spinal Cord Injury : Maximal Canal Compromise on Magnetic Resonance Imaging

Lee S, Roh SW, Jeon SR, Park JH, Kim KT, Lee YS, Cho DC

Objective : The period of mechanical ventilator (MV)-dependent respiratory failure after cervical spinal cord injury (CSCI) varies from patient to patient. This study aimed to identify predictors of MV at...
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Cephalic Vein Supercharging to Prevent Venous Congestion for a Reverse Radial Forearm Flap Used in the Reconstruction of Dorsum of Hand: A Case Report

Kim JL, Chun JY, Lee NH, Shin JY, Roh SG

The reverse radial forearm flap is often co-opted for soft tissue reconstruction of the dorsum of hand. Venous congestion can lead to flap necrosis or failure. To improve dorsum hand...
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Optimal Ratio of Wnt3a Expression in Human Mesenchymal Stem Cells Promotes Axonal Regeneration in Spinal Cord Injured Rat Model

Yoon HH, Lee HJ, Min J, Kim JH, Park JH, Kim JH, Kim SW, Lee H, Jeon SR

Objective : Through our previous clinical trials, the demonstrated therapeutic effects of MSC in chronic spinal cord injury (SCI) were found to be not sufficient. Therefore, the need to develop...
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Region-Specific Differences in the Apoe4-dependent Response to Focal Brain Injury

Lee SE, Yang H, Sung Y, Kim Y, Park SA

  • KMID: 2519890
  • Exp Neurobiol.
  • 2021 Aug;30(4):285-293.
  • doi: 10.5607/en21022
Apolipoprotein E (apoE) plays a role in various physiological functions including lipid transport, synaptic plasticity, and immune modulation. Epidemiological studies suggest that the apoE4 allele increases the risk of post-traumatic sequelae....
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Characteristics of alcohol-related non-traffic accident trauma patients

Eo SJ, Lee SH, Seo YW, Kim GM, Jang TC, Ko SH

  • KMID: 2519735
  • J Korean Soc Emerg Med.
  • 2021 Aug;32(4):307-314.
Objective: The purpose of this study was to analyze the characteristics of alcohol-related non-traffic accident trauma patients. Methods: A total of 2,582 non-traffic accident patients, above 16 years old, who visited...
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Effectiveness of Neurodynamic Mobilization versus Conventional Therapy on Spasticity Reduction and Upper Limb Function in Tetraplegic Patients

Saxena A, Sehgal S, Jangra MK

Study Design: The study employed a pre- and post-test experimental design. Purpose: This study was designed to assess the effect of neurodynamic mobilization of the median nerve on upper limb spasticity...
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Traumatic Hemothorax Caused by Thoracic Wall and Intrathoracic Injuries: Clinical Outcomes of Transcatheter Systemic Artery Embolization

Lee CM, Jeon CH, Lee R, Kwon H, Kim CW, Kim JH, Kim JH, Kim H, Kim SH, Lee CK, Park CY, Bae M

Purpose We aimed to assess the clinical efficacy of transcatheter arterial embolization (TAE) for treating hemothorax caused by chest trauma. Materials and Methods Between 2015 and 2019, 68 patients (56 male;...
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Imaging Features and Interventional Treatment for Liver Injuries and Their Complications

Yu SH, Park SH, Kim JW, Kim JH, Hwang JH, Park S, Lee KH

Liver injury is a common consequence of blunt abdominopelvic trauma. Contrast-enhanced CT allows for the rapid detection and evaluation of liver injury. The treatment strategy for blunt liver injury has...
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Diagnosis and treatment of nerve injury following venipuncture - A report of two cases -

Kim IJ, Cho H, Yi MS, Park YH, Kim S, Kim DK, Shin HY

Background: Venipuncture is one of the one of the most commonly performed, minimally-invasive procedures; however, it may lead to peripheral nerve injury. Here, we describe the diagnosis, treatment, and prognosis...
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Autoimmune Hemolytic Anemia Combined with Sepsis After Abdominal Trauma Surgery

Moon GS, Choi YU, Shim H, Jang JY

Intra-abdominal infection is a common, serious complication in patients undergoing emergency abdominal surgery following blunt abdominal trauma. Infectious conditions increase the incidence of autoimmune hemolytic anemia (AIHA), but reports of...
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Finding new indicators for operation and angiographic embolization in blunt renal injury patients: a single-center experience over 13 years

Ha G, Jang SW, Shin IS, Bang HJ, An S, Bae KS, Jang JY, Kim YW, Kim K

Purpose: Traumatic kidney injury can be treated surgically or nonsurgically. Nonsurgical treatment options include angiography, embolization, and conservative treatment. We aimed to identify factors that help in making clinical decisions...
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Physical and Biological Characteristics of Particle Therapy for Oncologists

Byun HK, Han MC, Yang K, Kim JS, Yoo GS, Koom WS, Kim YB

Particle therapy is a promising and evolving modality of radiotherapy that can be used to treat tumors that are radioresistant to conventional photon beam radiotherapy. It has unique biological and...
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