- Bilirubin protects grafts against nonspecific inflammation-induced injury in syngeneic intraportal islet transplantation
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Zhu H, Wang J, Jiang H, Ma Y, Pan S, Reddy S, Sun X
- KMID: 994397
- Exp Mol Med.
- 2010 Nov;42(11):739-748.
- doi: 10.3858/emm.2010.42.11.075
Nonspecific inflammatory response is the major cause for failure of islet grafts at the early phase of intraportal islet transplantation (IPIT). Bilirubin, a natural product of heme catabolism, has displayed... -
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- Celastrol inhibits production of nitric oxideandproinflammatory cytokines through MAPK signal transduction and NF-kappaB in LPS-stimulated BV-2 microglial cells
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Jung HW, Chung YS, Kim YS, Park YK
- KMID: 1091066
- Exp Mol Med.
- 2007 Dec;39(6):715-721.
Excessive production of nitric oxide (NO) and proinflammatory cytokines from activated microglia play an important role in human neurodegenerative disorders. Here, we investigated whether celastrol, which has been used as... -
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