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Liquid Chromatography-Mass Spectrometry-Based In Vitro Metabolic Profiling Reveals Altered Enzyme Expressions in Eicosanoid Metabolism

Lee SH, Kim EJ, Lee DH, Lee WY, Chung BC, Seo HS, Choi MH

BACKGROUND: Eicosanoids are metabolites of arachidonic acid that are rapidly biosynthesized and degraded during inflammation, and their metabolic changes reveal altered enzyme expression following drug treatment. We developed an eicosanoid...
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Inflammatory and Tumor Stimulating Responses after Laparoscopic Sigmoidectomy

Kim JS, Hur H, Min BS, Lee KY, Chung HC, Kim NK

PURPOSE: Laparoscopic colectomy has clinical benefits such as short hospital stay, less postoperative pain, and early return of bowel function. However, objective evidence of its immunologic and oncologic benefits is...
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