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Influence of Psychotropic Pro Re Nata Drug Use on Outcomes in Hospitalized Patients with Schizophrenia

Kyou Y, Oishi S, Takizawa T, Yoshimura Y, Hashimoto I, Suzuki R, Demizu R, Ono T, Noguchi Y, Kimura T, Inada K, Miyaoka H

Objective: In the treatment of patients with schizophrenia, pro re nata (PRN) drugs are commonly prescribed for medical indications such as agitation, acute psychiatric symptoms, insomnia, and anxiety. However, high-quality...
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Clozapine Is Better Tolerated in Younger Patients: Risk Factors for Discontinuation from a Nationwide Database in Japan

Toyoda K, Hata T, Yamauchi S, Kinoshita S, Nishihara M, Uchiyama K, Inada K, Kanazawa T

Objective The effectiveness of clozapine is clearly superior to other antipsychotics in the treatment of refractory schizophrenia. Clozapine leads to various side effects, and therefore many patients are forced to...
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Basic Verification of β-D Glucan in Leukocyte-Rich Plasma for the Diagnosis of Deep Mycosis

Shimoyama K, Kan S, Takahashi G, Morino G, Yamada Y, Inoue YI, Inada K, Endo S

Background: Currently, supplementary serological testing for β-D glucan (BDG) is often selected to diagnose deep mycosis in care covered by the health insurance in Japan. The Wako method used by...
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Cytokeratin 13, Cytokeratin 17, and Ki-67 Expression in Human Acquired Cholesteatoma and Their Correlation With Its Destructive Capacity

Hamed MA, Nakata S, Shiogama K, Suzuki K, Sayed RH, Nishimura , Iwata N, Sakurai K, Badawy BS, Inada K, Tsuge H, Tsutsumi Y

OBJECTIVES: Cholesteatoma is a nonneoplastic destructive lesion of the temporal bone with debated pathogenesis and bone resorptive mechanism. Both molecular and cellular events chiefly master its activity. Continued research is...
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Modified Open-Door Laminoplasty Using a Ceramic Spacer and Suture Fixation for Cervical Myelopathy

Ozawa T, Toyone T, Shiboi R, Inada K, Oikawa Y, Takahashi , Ohtori S, Inoue G, Miyagi M, Ishikawa T, Shirahata , Kudo Y, Inagaki K

PURPOSE: To introduce a new simple technique using suture anchors and ceramic spacers to stabilize the elevated laminae in open-door cervical laminoplasty. Although ceramic spacers were placed in the opened...
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