- The Role of Inflammasome-Associated Innate Immune Receptors in Cancer
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Dawson RE, Jenkins BJ
- KMID: 2562623
- Immune Netw.
- 2024 Oct;24(5):e38.
- doi: 10.4110/in.2024.24.e38
Dysregulated activation of the innate immune system is a critical driver of chronic inflammation that is associated with at least 30% of all cancers. Innate immunity can also exert tumour-promoting... -
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- Current Developments in NK Cell Engagers for Cancer Immunotherapy: Focus on CD16A and NKp46
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Shin MH, Oh E, Minn D
- KMID: 2562619
- Immune Netw.
- 2024 Oct;24(5):e34.
- doi: 10.4110/in.2024.24.e34
NK cells are specialized immune effector cells crucial for triggering immune responses against aberrant cells. Although recent advancements have concentrated on creating or releasing T-cell responses specific to tumor Ags,... -
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- Th Pathways in Immune-Mediated Skin Disorders: A Guide for Strategic Treatment Decisions
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Speeckaert R, Belpaire A, Lambert J, Speeckaert M, Geel Nv
- KMID: 2562618
- Immune Netw.
- 2024 Oct;24(5):e33.
- doi: 10.4110/in.2024.24.e33
In recent years, there have been significant breakthroughs in the identification of immunological components of skin diseases and in the development of immunomodulatory drugs. Novel therapies create exciting prospects for... -
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- Efficient In Vitro Plasma Cell Differentiation by B Cell Receptor Activation and Cytokine Stimulation
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Song HS, Kim YM
- KMID: 2562620
- Immune Netw.
- 2024 Oct;24(5):e35.
- doi: 10.4110/in.2024.24.e35
Plasma cells (PCs) constitute a small proportion of B cells, limiting their biochemical characterization. An in vitro culture system that reliably generates PCs could provide an alternative method to obtain... -
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- STING-STAT6 Signaling Pathway Promotes IL-4+ and IFN-α+ Fibrotic T Cell Activation and Exacerbates Scleroderma in SKG Mice
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Lee KH, Woo JS, Jeong HY, Choi JW, Bang CH, Youn J, Park SH, Cho ML
- KMID: 2562622
- Immune Netw.
- 2024 Oct;24(5):e37.
- doi: 10.4110/in.2024.24.e37
Systemic sclerosis (SS) is an autoimmune disease and pathological mechanisms of SS are unclear. In this study, we investigated the role of T cells in the progression of SS using... -
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- Increased Inflammatory Responses in Patients With Active Disseminated Non-Tuberculous Mycobacterial Infection and High Anti-InterferonGamma Autoantibodies
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Srisai P, Hongsa C, Hinwan Y, Manbenmad V, Chetchotisakd P, Anunnatsiri S, Faksri K, Techo T, Salao K, Edwards SW, Nithichanon A
- KMID: 2562621
- Immune Netw.
- 2024 Oct;24(5):e36.
- doi: 10.4110/in.2024.24.e36
Adult-onset immunodeficiency (AOID) is associated with the presence of anti-IFN-γ autoantibodies (auAbs). In disseminated nontuberculous mycobacterial (dNTM) infection with AOID, neutralization of IFN-γ by auAb may play a role in... -
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