- Extracellular Mechanisms of Neutrophils in Immune Cell Crosstalk
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Shrestha S, Hong CW
- KMID: 2549204
- Immune Netw.
- 2023 Oct;23(5):e38.
- doi: 10.4110/in.2023.23.e38
Neutrophils are professional phagocytes that provide defense against invading pathogens through phagocytosis, degranulation, generation of ROS, and the formation of neutrophil extracellular traps (NETs). Although long been considered as short-lived... -
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- The Role of CD4 T Cell Help in CD8 T Cell Differentiation and Function During Chronic Infection and Cancer
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Topchyan P, Lin S, Cui W
- KMID: 2549207
- Immune Netw.
- 2023 Oct;23(5):e41.
- doi: 10.4110/in.2023.23.e41
CD4 and CD8 T cells are key players in the immune response against both pathogenic infections and cancer. CD4 T cells provide help to CD8 T cells via multiple mechanisms,... -
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- Glucocorticoids Impair the 7α-Hydroxycholesterol-Enhanced Innate Immune Response
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Son Y, Kim BY, Kim M, Kim J, Kwon RJ, Kim K
- KMID: 2549206
- Immune Netw.
- 2023 Oct;23(5):e40.
- doi: 10.4110/in.2023.23.e40
Glucocorticoids suppress the vascular inflammation that occurs under hypercholesterolemia, as demonstrated in an animal model fed a high-cholesterol diet. However, the molecular mechanisms underlying these beneficial effects remain poorly understood.... -
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- Comprehensive Transcriptomic Analysis for Thymic Epithelial Cells of Aged Mice and Humans
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Lee S, Song SG, Chung DH
- KMID: 2549202
- Immune Netw.
- 2023 Oct;23(5):e36.
- doi: 10.4110/in.2023.23.e36
Thymic epithelial cells (TECs) play a critical role in thymic development and thymopoiesis. As individuals age, TECs undergo various changes that impact their functions, leading to a reduction in cell numbers... -
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- NADPH Oxidase 4-mediated Alveolar Macrophage Recruitment to Lung Attenuates Neutrophilic Inflammation in Staphylococcus aureus Infection
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Han S, Moon S, Chung YW, Ryu JH
- KMID: 2549218
- Immune Netw.
- 2023 Oct;23(5):e42.
- doi: 10.4110/in.2023.23.e42
When the lungs are infected with bacteria, alveolar macrophages (AMs) are recruited to the site and play a crucial role in protecting the host by reducing excessive lung inflammation. However, the... -
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- Combined Treatment With TGF-β1, Retinoic Acid, and Lactoferrin Robustly Generate Inducible Tregs (iTregs) Against High Affinity Ligand
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Jang YS, Park SH, Kang SG, Lee JS, Ko HJ, Kim PH
- KMID: 2549203
- Immune Netw.
- 2023 Oct;23(5):e37.
- doi: 10.4110/in.2023.23.e37
Forkhead box P3-positive (Foxp3 + )-inducible Tregs (iTregs) are readily generated by TGF-β1 at low TCR signaling intensity. TGF-β1–mediated Foxp3 expression is further enhanced by retinoic acid (RA) and lactoferrin... -
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- COVID-19 Vaccination Alters NK Cell Dynamics and Transiently Reduces HBsAg Titers Among Patients With Chronic Hepatitis B
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Shin H, Lee HS, Noh JY, Koh JY, Kim SY, Park J, Chung SW, Hur MH, Park MK, Lee YB, Kim YJ, Yoon JH, Ko JH, Peck KR, Song JY, Shin EC, Lee JH
- KMID: 2549205
- Immune Netw.
- 2023 Oct;23(5):e39.
- doi: 10.4110/in.2023.23.e39
Coronavirus disease 2019 (COVID-19) vaccination may non-specifically alter the host immune system. This study aimed to evaluate the effect of COVID-19 vaccination on hepatitis B surface Ag (HBsAg) titer and... -
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