- Pathophysiological Role of TLR4 in Chronic Relapsing Itch Induced by Subcutaneous Capsaicin Injection in Neonatal Rats
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Kim HJ, Lee EH, Lim YH, Jeong D, Na HS, Jung Y
- KMID: 2536247
- Immune Netw.
- 2022 Apr;22(2):e20.
- doi: 10.4110/in.2022.22.e20
Despite the high prevalence of chronic dermatitis and the accompanied intractable itch, therapeutics that specifically target itching have low efficacy. Increasing evidence suggests that TLRs contribute to immune activation and... -
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- Mitochondrial Transplantation Ameliorates the Development and Progression of Osteoarthritis
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Lee AR, Woo JS, Lee SY, Na HS, Cho KH, Lee YS, Lee JS, Kim SA, Park SH, Kim SJ, Cho ML
- KMID: 2536241
- Immune Netw.
- 2022 Apr;22(2):e14.
- doi: 10.4110/in.2022.22.e14
Osteoarthritis (OA) is a common degenerative joint disease characterized by breakdown of joint cartilage. Mitochondrial dysfunction of the chondrocyte is a risk factor for OA progression. We examined the therapeutic... -
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- Change of Dendritic Cell Subsets Involved in Protection Against Listeria monocytogenes Infection in ShortTerm-Fasted Mice
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Ju YJ, Lee KM, Kim G, Kye YC, Kim HW, Chu H, Park BC, Cho JH, Chang PS, Han SH, Yun CH
- KMID: 2536243
- Immune Netw.
- 2022 Apr;22(2):e16.
- doi: 10.4110/in.2022.22.e16
The gastrointestinal tract is the first organ directly affected by fasting. However, little is known about how fasting influences the intestinal immune system. Intestinal dendritic cells (DCs) capture antigens, migrate... -
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- Cytokine Inductions and Intracellular Signal Profiles by Stimulation of dsRNA and SEB in the Macrophages and Epithelial Cells
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Choi JP, Losol P, Ayoub G, Ji M, Kim SH, Cho SH, Chang YS
- KMID: 2536242
- Immune Netw.
- 2022 Apr;22(2):e15.
- doi: 10.4110/in.2022.22.e15
Foreign molecules, including viruses and bacteria-derived toxins, can also induce airway inflammation. However, to the best of our knowledge, the roles of these molecules in the development of airway inflammation... -
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- Obesity Exacerbates Coxsackievirus Infection via Lipid-Induced Mitochondrial Reactive Oxygen Species Generation
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Kim SR, Song JH, Ahn JH, Jeong MS, Yang YM, Cho J, Jeong JH, Cha Y, Kim KN, Kim HP, Chang SY, Ko HJ
- KMID: 2536246
- Immune Netw.
- 2022 Apr;22(2):e19.
- doi: 10.4110/in.2022.22.e19
Coxsackievirus B3 (CVB3) infection causes acute pancreatitis and myocarditis. However, its pathophysiological mechanism is unclear. Here, we investigated how lipid metabolism is associated with exacerbation of CVB3 pathology using high-fat... -
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- Dietary Diversity during Early Infancy Increases Microbial Diversity and Prevents Egg Allergy in High-Risk Infants
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Lee BR, Jung HI, Kim SK, Kwon M, Kim H, Jung M, Kyung Y, Kim BE, Choi SJ, Oh SY, Baek SY, Kim S, Bae J, Ahn K, Kim J
- KMID: 2536244
- Immune Netw.
- 2022 Apr;22(2):e17.
- doi: 10.4110/in.2022.22.e17
We aimed to investigate associations of dietary diversity (DD) with gut microbial diversity and the development of hen's egg allergy (HEA) in infants. We enrolled 68 infants in a highrisk... -
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- Impairment of Mitochondrial ATP Synthesis Induces RIPK3-dependent Necroptosis in Lung Epithelial Cells During Lung Injury by Lung Inflammation
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Lee SH, Shin JH, Park MW, Kim J, Chung KS, Na S, Ryu JH, Lee JH, Park MS, Kim YS, Moon JS
- KMID: 2536245
- Immune Netw.
- 2022 Apr;22(2):e18.
- doi: 10.4110/in.2022.22.e18
Dysfunction of mitochondrial metabolism is implicated in cellular injury and cell death. While mitochondrial dysfunction is associated with lung injury by lung inflammation, the mechanism by which the impairment of mitochondrial... -
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