- Mechanisms Underlying the Role of Myeloid-Derived Suppressor Cells in Clinical Diseases: Good or Bad
-
Ge Y, Cheng D, Jia Q, Xiong H, Zhang J
- KMID: 2518346
- Immune Netw.
- 2021 Jun;21(3):e21.
- doi: 10.4110/in.2021.21.e21
Myeloid-derived suppressor cells (MDSCs) have strong immunosuppressive activity and are morphologically similar to conventional monocytes and granulocytes. The development and classification of these cells have, however, been controversial. The activation... -
- CITED
-
- Close
- SHARE
-
- Close
- Toll-like Receptor 2 in Autoimmune Inflammation
-
Marks KE, Cho K, Stickling C, Reynolds JM
- KMID: 2518343
- Immune Netw.
- 2021 Jun;21(3):e18.
- doi: 10.4110/in.2021.21.e18
TLR signaling is critical for broad scale immune recognition of pathogens and/or danger molecules. TLRs are particularly important for the activation and the maturation of cells comprising the innate immune... -
- CITED
-
- Close
- SHARE
-
- Close
- Gut-Brain Connection: Microbiome, Gut Barrier, and Environmental Sensors
-
Gwak MG, Chang SY
- KMID: 2518345
- Immune Netw.
- 2021 Jun;21(3):e20.
- doi: 10.4110/in.2021.21.e20
The gut is an important organ with digestive and immune regulatory function which consistently harbors microbiome ecosystem. The gut microbiome cooperates with the host to regulate the development and function... -
- CITED
-
- Close
- SHARE
-
- Close
- Enriching CCL3 in the Tumor Microenvironment Facilitates T cell Responses and Improves the Efficacy of Anti-PD-1 Therapy
-
Kang TG, Park HJ, Moon J, Lee JH, Ha SJ
- KMID: 2518348
- Immune Netw.
- 2021 Jun;21(3):e23.
- doi: 10.4110/in.2021.21.e23
Chemokines are key factors that influence the migration and maintenance of relevant immune cells into an infected tissue or a tumor microenvironment. Therefore, it is believed that the controlled administration... -
- CITED
-
- Close
- SHARE
-
- Close
- Inhibition of Chitinase-3-like-1 by K284-6111 Reduces Atopic Skin Inflammation via Repressing Lactoferrin
-
Jeon SH, Lee YS, Yeo IJ, Lee HP, Yoon J, Son DJ, Han SB, Hong JT
- KMID: 2518347
- Immune Netw.
- 2021 Jun;21(3):e22.
- doi: 10.4110/in.2021.21.e22
Chitinase-3-like-1 (CHI3L1) is known to induce inflammation in the progression of allergic diseases. Previous our studies revealed that 2-({3-[2-(1-cyclohexen-1-yl)ethyl]-6,7-dimethoxy-4-oxo-3,4-dihydro-2-quinazolinyl}sulfanyl)-N-(4-ethylphenyl)butanamide (K284-6111; K284), the CHI3L1 inhibiting compound, has the anti-inflammatory effect on... -
- CITED
-
- Close
- SHARE
-
- Close
- The Role of Upper Airway Microbiome in the Development of Adult Asthma
-
Losol P, Choi JP, Kim SH, Chang YS
- KMID: 2518344
- Immune Netw.
- 2021 Jun;21(3):e19.
- doi: 10.4110/in.2021.21.e19
Clinical and molecular phenotypes of asthma are complex. The main phenotypes of adult asthma are characterized by eosinophil and/or neutrophil cell dominant airway inflammation that represent distinct clinical features. Upper... -
- CITED
-
- Close
- SHARE
-
- Close
- Effect of Human or Mouse IL-7 on the Homeostasis of Porcine T Lymphocytes
-
Hong JH, Kim SH, Kim HG, Jang JH, Son RG, Pack SP, Park YH, Kang P, Jeong KJ, Kim JS, Choi H, Kim SU, Jung YW
- KMID: 2518349
- Immune Netw.
- 2021 Jun;21(3):e24.
- doi: 10.4110/in.2021.21.e24
Due to the inconsistent fluctuation of blood supply for transfusion, much attention has been paid to the development of artificial blood using other animals. Although mini-pigs are candidate animals, contamination... -
- CITED
-
- Close
- SHARE
-
- Close
