- Experimental Animal Models of Coronavirus Infections: Strengths and Limitations
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Casel MAB, Rollon RG, Choi YK
- KMID: 2522158
- Immune Netw.
- 2021 Apr;21(2):e12.
- doi: 10.4110/in.2021.21.e12
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since the emergence of SARS-CoV-2 in the human population in late 2019, it has spread on... -
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- Nucleocapsid and Spike Proteins of SARS-CoV-2 Drive Neutrophil Extracellular Trap Formation
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Youn YJ, Lee YB, Kim SH, Jin HK, Bae Js, Hong CW
- KMID: 2522161
- Immune Netw.
- 2021 Apr;21(2):e16.
- doi: 10.4110/in.2021.21.e16
Patients with severe coronavirus disease 2019 (COVID-19) demonstrate dysregulated immune responses including exacerbated neutrophil functions. Massive neutrophil infiltrations accompanying neutrophil extracellular trap (NET) formations are also observed in patients with... -
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- Modulation of Pro-inflammatory and Anti-inflammatory Cytokines in the Fat by an Aloe Gel-based Formula, QDMC, Is Correlated with Altered Gut Microbiota
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An J, Lee H, Lee S, Song Y, Kim J, Park IH, Kong H, Kim K
- KMID: 2522162
- Immune Netw.
- 2021 Apr;21(2):e15.
- doi: 10.4110/in.2021.21.e15
Abnormal inflammatory responses are closely associated with intestinal microbial dysbiosis. Oral administration of Qmatrix-diabetes-mellitus complex (QDMC), an Aloe gel-based formula, has been reported to improve inflammation in type 2 diabetic... -
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- CD11b Deficiency Exacerbates Methicillin-Resistant Staphylococcus aureus-Induced Sepsis by Upregulating Inflammatory Responses of Macrophages
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Sim H, Jeong D, Kim HI, Pak S, Thapa B, Kwon HJ, Lee K
- KMID: 2522159
- Immune Netw.
- 2021 Apr;21(2):e13.
- doi: 10.4110/in.2021.21.e13
Macrophages are important for the first line of defense against microbial pathogens. Integrin CD11b, which is encoded by Itgam, is expressed on the surface of macrophages and has been implicated... -
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- Increase of Vδ2 + T Cells That Robustly Produce IL-17A in Advanced Abdominal Aortic Aneurysm Tissues
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Seo IH, Lee SJ, Noh TW, Kim JH, Joo HC, Shin EC, Park SH, Ko YG
- KMID: 2522163
- Immune Netw.
- 2021 Apr;21(2):e17.
- doi: 10.4110/in.2021.21.e17
Abdominal aortic aneurysm (AAA) is a chronic dilation of the aorta with a tendency to enlarge and eventually rupture, which constitutes a major cause of cardiovascular mortality. Although T-cell infiltrates have... -
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- Intranasal Vaccination with OuterMembrane Protein of Orientia tsutsugamushi induces Protective Immunity Against Scrub Typhus
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Park SM, Gu MJ, Ju YJ, Cheon IS, Hwang KJ, Gill B, Shim BS, Jeong HJ, Son YM, Choi S, Jeung W, Han SH, Chu H, Yun CH
- KMID: 2522160
- Immune Netw.
- 2021 Apr;21(2):e14.
- doi: 10.4110/in.2021.21.e14
Scrub typhus develops after the individual is bitten by a trombiculid mite infected with Orientia tsutsugamushi. Since it has been reported that pneumonia is frequently observed in patients with scrub... -
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